65798-59-6 Usage
General Description
2-(hydroxyimino)-N-pyridin-3-ylacetamide is a chemical compound with the molecular formula C8H8N4O2. It is an organic compound that contains a pyridine ring and an acetamide group, as well as a hydroxyimino functional group. This chemical has potential applications in the field of pharmaceuticals and agrochemicals due to its heterocyclic structure and functional groups. It may be used as a precursor in the synthesis of various biologically active compounds, and its structure makes it a potential candidate for drug development. Further research and experimentation may reveal additional uses and applications for 2-(hydroxyimino)-N-pyridin-3-ylacetamide.
Check Digit Verification of cas no
The CAS Registry Mumber 65798-59-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,7,9 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 65798-59:
(7*6)+(6*5)+(5*7)+(4*9)+(3*8)+(2*5)+(1*9)=186
186 % 10 = 6
So 65798-59-6 is a valid CAS Registry Number.
65798-59-6Relevant articles and documents
Synthesis and in vitro evaluation of bis-quaternary 2-(hydroxyimino)-N- (pyridin-3-yl)acetamide derivatives as reactivators against sarin and VX inhibited human acetylcholinesterase (hAChE)
Karade, Hitendra N.,Valiveti, Aditya Kapil,Acharya, Jyotiranjan,Kaushik, Mahabir Parshad
, p. 2684 - 2691 (2014)
A series of bis-quaternary pyridinium derivatives 3a-3i of 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide (2) have been synthesized. The synthesized pyridinium compounds have an amide group in conjugation to the oxime moiety. These compounds were evaluated in vitro for their reactivation efficacy against organophosphorus (OP) nerve agents (NAs) (sarin and VX) inhibited human erythrocyte ghost acetylcholinesterase (hAChE) and compared with the reactivation efficacy of 2-PAM and obidoxime. The pKa values of the synthesized compounds were found closer to the pKa values of 2- and 4-pyridinium oxime reactivators such as 2-PAM and obidoxime. Some of the compounds have shown better reactivation efficacy than 2-PAM, and obidoxime against sarin and VX inhibited AChE.
