658-08-2 Usage
Uses
Used in Organic Synthesis:
(3-FLUORO-PHENYL)-OXO-ACETONITRILE serves as a building block in organic synthesis, contributing to the creation of a wide array of organic compounds. Its presence in these syntheses is instrumental in developing new chemical entities with diverse applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3-FLUORO-PHENYL)-OXO-ACETONITRILE is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity play a crucial role in the development of new drugs and therapeutic agents.
Used in Production of Pharmaceutical Intermediates:
(3-FLUORO-PHENYL)-OXO-ACETONITRILE's properties make it suitable for the production of pharmaceutical intermediates, which are essential precursors in the synthesis of final drug products. Its contribution to this process is vital for advancing pharmaceutical development and innovation.
Used in Chemical Processes:
Beyond its applications in organic synthesis and pharmaceutical research, (3-FLUORO-PHENYL)-OXO-ACETONITRILE is also employed in other chemical processes. Its versatility and the unique properties imparted by the fluorine substituent make it a valuable asset in a range of chemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 658-08-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 658-08:
(5*6)+(4*5)+(3*8)+(2*0)+(1*8)=82
82 % 10 = 2
So 658-08-2 is a valid CAS Registry Number.
658-08-2Relevant academic research and scientific papers
A Cyanide-Free Synthesis of Acylcyanides through Ru-Catalyzed C(sp3)-H-Oxidation of Benzylic Nitriles
Eisele, Pascal,Bauder, Michael,Hsu, Shih-Fan,Plietker, Bernd
, p. 689 - 691 (2019/05/07)
A practical method for generation of acylcyanides devoid of any external cyanide sources is presented that relies on a mild Ru-catalyzed selective C?H-oxidation of benzylic nitriles. The starting materials are smoothly generated through condensation of the corresponding carboxylic acid amides using silanes. The obtained acylcyanides can be employed in a plethora of transformation as exemplified to some larger extend in the sequence of C?H-oxidation-Tischenko-rearrangement for the generation of structurally diverse benzoyloxycyanohydrines.
