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Methanesulfonamide, 1,1-difluoro-N-phenyl-, also known as 1,1-difluoro-N-phenylmethanesulfonamide, is an organic compound with the chemical formula C7H7F2NO2S. It is a derivative of methanesulfonamide, featuring a phenyl group attached to the nitrogen atom and two fluorine atoms bonded to the carbon atom adjacent to the sulfonamide group. Methanesulfonamide, 1,1-difluoro-N-phenyl- is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of herbicides and insecticides. Its chemical structure provides unique properties that can enhance the activity and selectivity of the final products. Due to its potential applications in the development of new chemicals, research on 1,1-difluoro-N-phenylmethanesulfonamide and its derivatives is an active area in the field of organic chemistry.

658-43-5

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658-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 658-43-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 658-43:
(5*6)+(4*5)+(3*8)+(2*4)+(1*3)=85
85 % 10 = 5
So 658-43-5 is a valid CAS Registry Number.

658-43-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,1-difluoro-N-phenylmethanesulfonamide

1.2 Other means of identification

Product number -
Other names Difluormethansulfonsaeure-anilid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:658-43-5 SDS

658-43-5Downstream Products

658-43-5Relevant academic research and scientific papers

A new synthesis of difluoromethanesulfonamides - A novel pharmacophore for carbonic anhydrase inhibition

Boyle, Nicholas A.,Chegwidden, W. Richard,Blackburn, G. Michael

, p. 222 - 224 (2007/10/03)

Preparation of the key intermediate carboxydifluoromethanesulfonamide provides direct synthetic access to a wide range of novel difluoromethanesulfonamides, including the acetazolamide analogue (2-ethanoylamino-1,3,4-thiadiazol-5-yl)-difluoromethanesulfonamide. Their water solubility and stability, ether partition coefficient, pK, and submicromolar dissociation constants for human carbonic anhydrase isozyme II (HCA II) make them promising candidates for topical glaucoma therapy.

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