6582-10-1Relevant articles and documents
Gold-catalyzed oxidative couplings of two indoles with one aryldiazo cyanide under oxidant-free conditions
Singh, Rahulkumar Rajmani,Liu, Rai-Shung
, p. 4593 - 4596 (2017)
Gold-catalyzed oxidative couplings of two indoles and one α-cyano gold carbene to form bis(indolyl)methane derivatives are described. Two different indoles are compatible with these reactions to provide reasonable yields. A plausible mechanism is postulated to rationalize the experimental data including product distributions, D2O labeling, and the significant effects of gold catalysts and cyano groups.
Gold-Catalyzed Oxidative Cross-Coupling Reactions among Two Distinct Arenes and One Gold Carbene with Phosphoric Acids as Cocatalysts
Patil, Manoj D.,Kale, Balaji S.,Liu, Rai-Shung
supporting information, p. 5658 - 5668 (2020/10/22)
Gold-catalyzed oxidative cross-coupling reactions of two distinct arenes with one gold carbene furnish triarylmethane products. Notably, competitive homo-coupling reactions are efficiently suppressed with a phosphoric acid as co-catalyst (10 mol%) in THF. These cross-coupling reactions have a wide scope of applicable substrates, with respect to indoles, arylamines, and α-aryl diazo cyanides or esters. Our mechanistic analysis indicates that the basicity of the arylanilines greatly affects the cross-coupling efficiency. (Figure presented.).
