65825-93-6Relevant articles and documents
SYNTHESIS OF POTENTIAL CYTOTOXIC QUATERNARY AMMONIUMS BY OXIDATION OF EBURNANE ALKALOIDS
Lewin, Guy,Schaeffer, Corinne,Pierre, Alain,Guilbaud, Nicolas,Atassi, Ghanem,Poisson, Jacques
, p. 2707 - 2722 (2007/10/02)
Oxidation of vincamine and substituted analogs on ring-A was carried out in two steps: benzylic oxidation by Jones reagent and aromatization of ring-C with Hg(OAc)2 or Tl(OCOCF3)3 in trifluoroacetic acid.Final compounds are quaternary ammoniums which exhibited weak cytotoxicity or no cytotoxicity according to substituents on ring-A and nature of ring-E.
Metabolism of vincamine hydrochloride in the rat
Vigano,Paracchini,Piacenza,Pesce
, p. 583 - 594,591, 593 (2007/10/09)
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