65840-58-6

Usage

Uses

Used in Pharmaceutical Synthesis:
Ethanone, 1-(6-methoxy-2-benzothiazolyl)(9CI) is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Dye Production:
In the dye industry, Ethanone, 1-(6-methoxy-2-benzothiazolyl)(9CI) serves as a key component in the production of dyes. Its chemical properties contribute to the development of dyes with specific color characteristics and stability.
Used in Organic Compound Synthesis:
Ethanone, 1-(6-methoxy-2-benzothiazolyl)(9CI) is employed as a building block in the synthesis of other organic compounds. Its versatility in chemical reactions enables the creation of a wide range of molecules with diverse applications.
Used in Medicinal Chemistry Research:
Due to its structural features and potential biological activities, Ethanone, 1-(6-methoxy-2-benzothiazolyl)(9CI) is an interesting target for research in medicinal chemistry. It may lead to the discovery of new drugs and therapeutic agents.

Upstream product

• 1747-60-0 6-methoxybenzothiazol-2-ylamine 
• 127-19-5 N,N-dimethyl acetamide 
• 2941-59-5 2-iodo-6-methoxybenzo[d]thiazole 
• 2942-13-4 6-methoxy-1,3-benzothiazole 
• 762-04-9 phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Peroxides as "switches" of dialkyl H-phosphonate: Two mild and metal-free methods for preparation of 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates

Two mild and metal-free methods for the preparation of two kinds of important benzothiazole derivatives, 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates, respectively, were developed. The dialkyl H-phosphonate (RO)2P(O)H exists i

Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors

The design, synthesis and structure activity relationship studies of a series of compounds from benzo[d]imidazo[5,1-b]thiazole scaffold as phosphodiesterase 10A (PDE10A) inhibitors are discussed. Several potent analogs with heteroaromatic substitutions (9a-d) were identified. The anticipated binding mode of these analogs was confirmed by performing the in silico docking experiments. Later, the heteroaromatics were substituted with saturated heteroalkyl groups which provided a tool compound 9e with excellent PDE10A activity, PDE selectivity, CNS penetrability and with favorable pharmacokinetic profile in rats. Furthermore, the compound 9e was shown to be efficacious in the MK-801 induced psychosis model and in the CAR model of psychosis.