65864-89-3

Basic information

• Product Name: C₁₀H₁₁N₃O
• Synonyms: C₁₀H₁₁N₃O
• CAS NO: 65864-89-3
• Molecular Weight: 189.217
• Mol File: 65864-89-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₁N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₁N₃O(65864-89-3)
• EPA Substance Registry System: C₁₀H₁₁N₃O(65864-89-3)

Safety Data

• Hazardous Substances Data: 65864-89-3(Hazardous Substances Data)

Upstream product

• 826-55-1 2-methyl-2-phenylpropionic acid 
• 36293-05-7 2-methyl-2-phenylpropanoyl chloride 

Downstream Products

• 4747-74-4 α,α-dimethylbenzyl isocyanate 
• 1161825-78-0 3-(1-phenyl-1methylethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 

Relevant articles and documents

Synthesis of Acyl Phosphoramidates Employing a Modified Staudinger Reaction

A one-step synthesis of acyl phosphoramidates from a variety of functionalized acyl azides has been developed employing trimethylsilyl chloride as an activating agent in a modified Staudinger reaction. The methodology was further adapted to include the in situ generation of the acyl azides from a diverse selection of carboxylic acids and hydrazide starting synthons. The reaction scope was extended to include the synthesis of imidodiphosphates and the natural product Microcin C.

3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO-[5,1-D][1,2,3,5-TETRAZINE-8-CARBOXYLIC ACID AMIDES AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain 3-substituted-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (collectively referred to herein as 3TM compounds). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.