65866-00-4

Upstream product

• 1117-71-1 methyl 4-bromocrotonate 
• 603-35-0 triphenylphosphine 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 72967-11-4 (3-methoxycarbonyl-2-propenyl)triphenylphosphonium bromide 

Downstream Products

• 67040-03-3 (2E,4E,6E)-7-[(1R,2R,3R,5S)-2-[(E)-4-Phenoxy-3-(tetrahydro-pyran-2-yloxy)-but-1-enyl]-3,5-bis-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hepta-2,4,6-trienoic acid methyl ester 
• 67039-95-6 (2E,4E,6E)-7-[(1R,2R,3R,5S)-2-[(E)-4-(3-Chloro-phenoxy)-3-(tetrahydro-pyran-2-yloxy)-but-1-enyl]-3,5-bis-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hepta-2,4,6-trienoic acid methyl ester 
• 106851-43-8 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-2,3,3a,6,7,7a-hexahydro-benzo[b]thiophene-6-carboxylic acid methyl ester 
• 85558-14-1 (E)-4-[(4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-but-2-enoic acid methyl ester 
• 85558-16-3 (E)-4-[(4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-but-3-enoic acid methyl ester 
• 28066-21-9 (±)-methyl (E)-2,4,5-tetradecatrienoate 
• 1443457-24-6 (5-methoxy-3-(methoxycarbonyl)-5-oxopent-2-en-1-yl)triphenylphosphonium bromide 
• 1167440-07-4 (2E,4Z)-methyl 5-benzamidopenta-2,4-dienoate 
• 1167440-08-5 (2E,4E)-methyl 5-benzamidopenta-2,4-dienoate 
• 97690-87-4 Methyl (2E,4E,6S,7S,8S)-7-hydroxy-6,8-dimethyl-9-triphenylmethoxy-2,4-nonadienoate 
• 104855-38-1 AK-toxin II methyl ester 
• 56495-90-0 methyl (2E,4E,6E)-7-phenylhepta-2,4,6-trienoate 

Relevant academic research and scientific papers

KM-01, a brassinolide inhibitor, its production, isolation and structure from two fungi Drechslera avenae and Pycnoporus coccineus

A new brassinolide inhibitor, named KM-01, was isolated from the culture filtrates of two fungal species, Drechslera avenae and Pycnoporus coccineus, and the structure with absolute stereochemistry was elucidated as the fatty acid ester of an eremophilane sesquiterpene, bipolaroxin, based on spectroscopic analysis, chemical degradation, and synthesis of the fatty acid. Copyright (C) 1998 Elsevier Science Ltd.

Fast and efficient one step synthesis of dienamides

A fast and efficient one-step approach to the synthesis of dienamides is reported. This concise methodology relies on the use of imides as reactive intermediates and allows for the preferential formation of Z,E-dienamides in good yields.

Dibasic inhibitors of human mast cell tryptase. Part 3: Identification of a series of potent and selective inhibitors containing the benzamidine functionality

A survey of charged groups and linkers for a series of symmetrical and unsymmetrical dibasic inhibitors is described, leading to several classes of potent and selective inhibitors. In particular, the benzamidine functionality was identified as the most potent charged group investigated.