658696-17-4

Upstream product

• 5427-82-7 1H-pyrrole-2-carbonyl chloride 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1193-62-0 methyl Pyrrole-2-carboxylate 

Downstream Products

• 658696-16-3 5-(1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-pyrrole-2-carboxylic acid ((S)-1-phenyl-ethyl)-amide 

Relevant academic research and scientific papers

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

3-PYRROLYL-PYRIDOPYRAZOLES AND 3-PYRROLYL-INDAZOLES AS NOVEL KINASE INHIBITORS

Compounds of Formula (I) are useful as mediators of protein kinases and have activity as cell proliferation inhibitors where X, R1-R7 and R9 are as defined herein.