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NORDIAZEPAM-D5, also known as the primary labeled metabolite of Diazepam, is a compound that acts as a ligand for the GABAA receptor benzodiazepine modulatory site. It is characterized by its anxiolytic properties and is classified as a controlled substance with depressant effects. NORDIAZEPAM-D5 is a beige solid.

65891-80-7

65891-80-7 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.

65891-80-7 Usage

Uses

Used in Pharmaceutical Industry:
NORDIAZEPAM-D5 is used as an anxiolytic agent for the treatment of anxiety disorders and related conditions. It works by modulating the GABAA receptor, leading to a calming effect on the central nervous system and providing relief from anxiety symptoms.
Used in Research and Development:
NORDIAZEPAM-D5 is used as a research tool for studying the mechanisms of action and interactions of benzodiazepines with the GABAA receptor. This helps in understanding the role of these compounds in various neurological and psychiatric conditions and aids in the development of new therapeutic strategies.
Used in Quality Control and Analytical Testing:
NORDIAZEPAM-D5 is used as a reference compound in the quality control and analytical testing of Diazepam and its metabolites. This ensures the accuracy and reliability of test results and helps in maintaining the safety and efficacy of Diazepam as a medication.
Used in Forensic Toxicology:
NORDIAZEPAM-D5 is used as a reference material in forensic toxicology for the identification and quantification of Diazepam and its metabolites in biological samples. This is crucial in cases involving drug-related fatalities, drug abuse, or legal disputes related to the use of benzodiazepines.

Check Digit Verification of cas no

The CAS Registry Mumber 65891-80-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,8,9 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 65891-80:
(7*6)+(6*5)+(5*8)+(4*9)+(3*1)+(2*8)+(1*0)=167
167 % 10 = 7
So 65891-80-7 is a valid CAS Registry Number.

65891-80-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-chloro-5-(2,3,4,5,6-pentadeuteriophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one

1.2 Other means of identification

Product number -
Other names Desmethyldiazepam-d5 solution

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65891-80-7 SDS

65891-80-7Downstream Products

65891-80-7Relevant academic research and scientific papers

Novel method for synthesizing D5-diazepam

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, (2021/06/09)

The invention discloses a novel method for synthesizing D5-diazepam, belongs to the field of organic chemistry, and can be applied to the field of forensic poison analysis. According to the method disclosed by the invention, 2-amino-5-chlorobenzyl cyanide and D5-phenylboronic acid are used as raw materials, and the D5-diazepam is obtained by carrying out addition, cyclization and methylation processes on cyano groups by palladium-catalyzed arylboronic acid and carrying out separation and purification. The method has the advantages of mild reaction conditions, short synthesis steps, high yield and the like, and the synthesized D5-diazepam has high purity and good stability and can be used as an internal standard substance for forensic poison analysis quality control to realize domestic substitution.