6590-82-5

Basic information

• Product Name: 4-Quinolinamine, 2-ethyl-1,2,3,4-tetrahydro-3-methyl-N-phenyl-
• CAS NO: 6590-82-5
• Molecular Formula: C18H22N2
• Molecular Weight: 266.386
• Mol File: 6590-82-5.mol

Chemical Properties

• CAS DataBase Reference: 4-Quinolinamine, 2-ethyl-1,2,3,4-tetrahydro-3-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinolinamine, 2-ethyl-1,2,3,4-tetrahydro-3-methyl-N-phenyl-(6590-82-5)
• EPA Substance Registry System: 4-Quinolinamine, 2-ethyl-1,2,3,4-tetrahydro-3-methyl-N-phenyl-(6590-82-5)

Safety Data

• Hazardous Substances Data: 6590-82-5(Hazardous Substances Data)

Upstream product

• 123-38-6 propionaldehyde 
• 62-53-3 aniline 
• 67832-70-6 (DL)-2-phenylamino-butyric acid 

Relevant articles and documents

Aluminosilicates with Different Porous Structures in the Synthesis of 2-Ethyl-3-Methylquinoline

Abstract: The catalytic properties of microporous zeolites of different structural types (FAU, BEA, MOR, and MFI), a micro–meso–macroporous zeolite (H-Ymmm), and an ASM mesoporous aluminosilicate in the reaction of aniline with propionic aldehyde have been studied. It has been found that the reaction proceeds with a high conversion of aniline (90–99% over zeolites and 71% over an ASM aluminosilicate) to form two main products, namely, 2-ethyl-3-methylquinoline (2) and 2-ethyl-3-methyl-N-phenyl-1,2,3,4-tetrahydroquinoline-4-amine (3). The most selective catalysts for the synthesis of quinoline 2 are H-Y (up to 64%) and H-Ymmm (59%) zeolites and the ASM aluminosilicate (50%). It has been shown that an increase in the quinoline 2 selectivity is promoted by an increase in the catalyst acidity, in the reaction temperature to 160°C, in the catalyst concentration to 20 wt %, and in the aniline : aldehyde molar ratio to 1 : 2.

Mesoporous Aluminosilicates in the Synthesis of N-Heterocyclic Compounds

Abstract: The catalytic properties of samples of amorphous mesoporous aluminosilicate ASM with different Si/Al molar ratios (40, 80, 160) were studied in the synthesis of practically important pyridines (by the interaction of С2–С5 alcohols with formaldehyde and ammonia, cyclocondensation of acetaldehyde and propionic aldehyde with ammonia), dialkylquinolines and alkyltetrahydroquinolines (by reaction of aniline with C3, C4 aldehydes) and alkyldihydroquinolines (by interaction of aniline with ketones, acetone and acetophenone). It is found that mesoporous aluminosilicate ASM sample with a molar ratio of Si/Al = 40, which has the highest acidity among the studied samples, exhibits the highest activity and selectivity in these reactions.

Sequential Photoredox Catalysis for Cascade Aerobic Decarboxylative Povarov and Oxidative Dehydrogenation Reactions of N-Aryl α-Amino Acids

A visible-light-driven sequential photoredox catalysis to allow N-aryl α-amino acids to experience efficient cascade aerobic decarboxylative Povarov and oxidative dehydrogenation (ODH) reactions is described. With a dicyanopyrazine-derived chromophore (DP

Method for synthesizing 1,2,3,4-tetrahydroquinoline compounds in mode that decarboxylation of amino acid is catalyzed by visible light

The invention relates to a method for synthesizing 1,2,3,4-tetrahydroquinoline compounds in the mode that decarboxylation of amino acid is catalyzed by visible light. The method is characterized in that in an air atmosphere, the N-phenyl amino acidic compounds shown in the formula I, an organic photocatalyst DPZ and 4-molecular sieve are dissolved in an organic solvent, stirred and reacted for atleast 5 hours at the temperature of 20-30 DEG C under the irradiation of the visible light, separation and purification are conducted, and then the tetrahydroquinoline compounds shown in the formula II are obtained, wherein in the formula I and the formula II (the formulas are shown in the description), R is representative for any one of hydrogen, halogen, alkyl, phenyl and alkoxy, R1 is representative for any one of hydrogen, methyl, n-propyl and phenyl, alkyl is representative for methyl or ethyl or normal-butyl or benzyl, and aryl is representative for substituted phenyl or 4-tert-butyl phenyl. According to the method, substrates are simple, reaction conditions are mild, the usage amount of the catalyst is low, the yield is high, and no metal participates in a reaction.

TETRAHYDROQUINOLINES AS AGONISTS OF LIVER-RECEPTORS

The present invention relates to specific compounds and pharmaceutically acceptable salts thereof; methods for synthesizing these compounds; compositions comprising at least one of these compounds or a pharmaceutically acceptable salt thereof; and methods