67832-70-6

Basic information

• Product Name: 2-(phenylamino)butanoic acid
• CAS NO: 67832-70-6
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.2157
• Mol File: 67832-70-6.mol

Chemical Properties

• Boiling Point: 363.8°C at 760 mmHg
• Flash Point: 173.8°C
• Density: 1.168g/cm³
• Vapor Pressure: 6.27E-06mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 2-(phenylamino)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylamino)butanoic acid(67832-70-6)
• EPA Substance Registry System: 2-(phenylamino)butanoic acid(67832-70-6)

Safety Data

• Hazardous Substances Data: 67832-70-6(Hazardous Substances Data)

Usage

Derivative of

GABA (gamma-aminobutyric acid)

Usage

Precursor in the synthesis of various drugs and pharmaceuticals

Potential properties

Neuroprotective, anti-convulsant

Possible applications

Treatment of anxiety and mood disorders

Unique feature

Phenylamino group attached to the second carbon of the butanoic acid chain

Upstream product

• 62-53-3 aniline 
• 533-68-6 2-bromobutyric acid ethyl ester 
• 591-50-4 iodobenzene 
• 2835-81-6 2-aminobutanoic acid 
• 124-38-9 carbon dioxide 
• 123-38-6 propionaldehyde 
• 586-96-9 Nitrosobenzene 
• 99940-43-9 C₁₆H₂₉NO₃Si₂ 
• 80-58-0 2-Bromobutyric acid 
• 74-90-8 hydrogen cyanide 

Downstream Products

• 6590-82-5 2-ethyl-3-methyl-N-phenyl-1,2,3,4-tetrahydroquinoline-4-amine 
• 5278-43-3 3-methyl-2-phenyl-quinoline 
• 34394-93-9 4-ethyl-3-phenyl-sydnone 
• 91880-52-3 2-(N-nitroso-anilino)-butyric acid 

Relevant articles and documents

Integrated Flow Synthesis of α-Amino Acids byIn SituGeneration of Aldimines and Subsequent Electrochemical Carboxylation

The synthesis of α-amino acids was carried out in a continuous flow system. In this system, aldimines were efficiently generatedin situvia the dehydration-condensation of aldehydes with anilines in a desiccant bed column filled with 4 ? molecular sieves d

Copper-catalyzed aryl amination in aqueous media with 2- dimethylaminoethanol ligand

Copper-catalyzed amination of aryl bromides and iodides under mild conditions has been developed with 2-dimethylaminoethanol as ligand and water as solvent. A variety of hydrophilic and hydrophobic aryl halide substrates have been aminated in good yield with a variety of amino acids, amino alcohols and peptides. This method has successfully N-arylated some hydrophilic amino compounds not available by other methods.