65905-96-6

Basic information

• Product Name: methyl 5-fluoro-4-methoxy-2,6-dioxohexahydropyrimidine-5-carboxylate
• CAS NO: 65905-96-6
• Molecular Formula: C₇H₉FN₂O₅
• Molecular Weight: 220.1552
• Mol File: 65905-96-6.mol
• Article Data: 3

Chemical Properties

• Density: 1.45g/cm³
• Refractive Index: 1.487
• CAS DataBase Reference: methyl 5-fluoro-4-methoxy-2,6-dioxohexahydropyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-fluoro-4-methoxy-2,6-dioxohexahydropyrimidine-5-carboxylate(65905-96-6)
• EPA Substance Registry System: methyl 5-fluoro-4-methoxy-2,6-dioxohexahydropyrimidine-5-carboxylate(65905-96-6)

Safety Data

• Hazardous Substances Data: 65905-96-6(Hazardous Substances Data)

Upstream product

• 28485-17-8 5-carbethoxyuracil 
• 42821-92-1 methyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 373-91-1 hypofluorous acid trifluoromethyl ester 
• 65696-20-0 methyl ureidomethylenemalonate 
• 65726-47-8 5-fluoro-6-hydroxy-5-methoxycarbonyl-5,6-dihydrouracil 
• 38026-46-9 ethyl 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxilate 
• 67-56-1 methanol 
• 65905-97-7 5-ethoxycarbonyl-5-fluoro-6-hydroxy-5,6-dihydrouracil 
• 65906-09-4 4-acetoxy-5-fluoro-2,6-dioxo-hexahydro-pyrimidine-5-carboxylic acid methyl ester 

Downstream Products

• 51-21-8 5-fluorouracil 

Relevant articles and documents

Uracil derivatives and production thereof

New derivatives of the formula: STR1 (wherein X is O or NH; R1 is --OH which may optionally be etherified or esterified, etherified mercapto or --NH2 which may optionally be substituted; R2 and R3, respectively, mean H, lower alkyl or STR2 and Y is an esterified or amidated carboxyl group, or CN). These derivatives are produced, by fluorination of corresponding 1,2,3,4-tetrahydro-2,4-dioxopyrimidine compounds and can be converted into 5-fluorouracil derivatives under hydrolytic conditions. The new derivatives are able to prolong the lives of animals having carcinomas or have antiviral activity.

Studies on fluorinated pyrimidines. I. A new method of synthesizing 5-fluorouracil and its derivatives

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