65964-60-5

Basic information

• Product Name: 2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE
• Synonyms: 2-(4-METHYLPHENYL)IMIDAZO[1,2-A]PYRIDINE;2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE
• CAS NO: 65964-60-5
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• Mol File: 65964-60-5.mol
• Article Data: 89

Chemical Properties

• Melting Point: 144-145 °C
• Appearance: /
• Density: 1.11 g/cm³
• Refractive Index: 1.626
• Storage Temp.: 2-8°C
• PKA: 6.77±0.50(Predicted)
• CAS DataBase Reference: 2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE(65964-60-5)
• EPA Substance Registry System: 2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE(65964-60-5)

Safety Data

• Hazardous Substances Data: 65964-60-5(Hazardous Substances Data)

Usage

General Description

2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE is a chemical compound with the molecular formula C15H12N2. It belongs to the class of imidazo[1,2-a]pyridine derivatives and is a heterocyclic compound containing both imidazole and pyridine rings. 2-P-TOLYL-IMIDAZO[1,2-A]PYRIDINE has potential applications in the pharmaceutical industry, particularly in the development of new drugs and medications. It may have therapeutic properties and could be used in the treatment of various medical conditions. Its precise uses and properties are still under study, but it has shown promise as a potential drug candidate in preclinical research. Additionally, this compound could have applications in other fields such as materials science and organic synthesis. However, further research and testing are needed to fully understand and utilize its potential benefits.

InChI:InChI=1/C14H12N2/c1-11-5-7-12(8-6-11)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3

Upstream product

• 504-29-0 2-aminopyridine 
• 98475-04-8 1-(4-methylphenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 17282-38-1 1-(4-methylphenacyl)pyridinium bromide 
• 110-86-1 pyridine 
• 619-41-0 4-(bromoacetyl)toluene 
• 40805-62-7 2-iodo-1-(4-methylphenyl)ethanone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 104-87-0 4-methyl-benzaldehyde 
• 766-97-2 4-n-methylphenylacetylene 
• 622-96-8 4-methylethylbenzene 
• 2089-33-0 4-methylacethophenone oxime 
• 96475-75-1 4‐methylacetophenone oxime acetate 
• 4209-24-9 p-methylphenacyl chloride 
• 60672-33-5 4-methyl-N'-(1-(p-tolyl)ethylidene)benzenesulfonohydrazide 

Downstream Products

• 3369-10-6 4-((2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methyl)morpholine 
• 349482-08-2 2-chloro-2,2-difluoro-1-(2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-ethanone 
• 365213-41-8 N,N-dimethyl-1-(2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine 
• 1310492-81-9 2-(p-tolyl)-3-(phenylthio)imidazo[1,2-a]pyridine 
• 1463476-28-9 1-ethyl-2-(4-tolyl)imidazo[1,2-a]pyridinium iodide 
• 142016-38-4 2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-carbaldehyde 

Relevant articles and documents

A multi pathway coupled domino strategy: I2/ TBHP-promoted synthesis of imidazopyridines and thiazoles via sp3, sp2 and sp C-H functionalization

I2/TBHP-promoted, one-pot, multi pathway synthesis of imidazopyridines and thiazoles has been achieved through readily available ethylarenes, ethylenearenes and ethynearenes. I2/TBHP as an initiator and oxidant is used to realize the C-H functionalization of this domino reaction. Simple and available starting materials, wide range of functional group tolerance, high potential for drug activity of the products and application in production are the advantageous features of this method.

Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry

The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.