65967-52-4

Usage

Uses

Used in Pharmaceutical Industry:
2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylideneis used as a building block for the synthesis of complex pharmaceutical compounds. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylideneis used as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties can contribute to the development of more effective and environmentally friendly products.
Used in Materials Science:
2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylideneis used in materials science for the development of new materials with specific properties. Its unique structure and reactivity can be leveraged to create materials with improved performance in various applications, such as coatings, adhesives, and polymers.

Upstream product

• 78-19-3 3,9-divinyl-2,4,8,10-tetraoxaspiro-[5.5]undecane 

Relevant academic research and scientific papers

Tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug, nano-micelle thereof, preparation method of tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug and application of nano-micelle

The invention discloses a tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug. The tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug has a structure shown as formula (I), wherein, when m=1 or m=0, different expressions are achieved, R represents -CH3 or -CH2CH3, L1 and L2 mutually independently represent Cl, N3 and NO3, or n is 10-80. The invention also discloses a preparation method of the tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug. The preparation method comprises the step of reacting a double-hydroxyl axially-coordinated tetravalent platinum compound with a dicyclic double-bond orthoester precursor. Besides, the invention also discloses a nano-micelle composed of the tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug and application of the nano-micelle. The tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug has the advantages that the tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug and the composed nano-micelle achieve pH hypersensitivity and reduction dual responsiveness; a new anti-tumor nano-drug prepared from the tetravalent platinum compound-dicyclic double-bond amphiphilic polymer prodrug is high in biodegradability, excellent in tumor cell toxicity, relatively long-term in blood circulation stability and capable of achieving certain tumor targeting functionality.

METHOD OF PREPARING DI(KETENE ACETALS)

Di(ketene acetals) are prepared by photoisomerizing the corresponding di(vinyl acetals).