78-19-3 Usage
Chemical Properties
white crystals or crystalline mass
Uses
Different sources of media describe the Uses of 78-19-3 differently. You can refer to the following data:
1. 3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane is an acetal-type crosslinking agent comonomer and has been used in radical emulsion copolymerization of 2-hydroxyethyl methacrylate. As cross-linking agent in the synthesis of acid-degradable core-crosslinked micelles, 3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane can be used in the synthesis of new biocompatible copolymer for loading the indomethacin as drug model.
2. 3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane is an acetal-type crosslinking agent comonomer and has been used: in radical emulsion copolymerization of 2-hydroxyethyl methacrylateas cross-linking agent in the synthesis of acid-degradable core-crosslinked micelles in the synthesis of new biocompatible copolymer for loading the indomethacin as drug model
Check Digit Verification of cas no
The CAS Registry Mumber 78-19-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 78-19:
(4*7)+(3*8)+(2*1)+(1*9)=63
63 % 10 = 3
So 78-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H16O4/c1-3-9-12-5-11(6-13-9)7-14-10(4-2)15-8-11/h3-4,9-10H,1-2,5-8H2
78-19-3Relevant articles and documents
Unlocking the Potential of Poly(Ortho Ester)s: A General Catalytic Approach to the Synthesis of Surface-Erodible Materials
Tschan, Mathieu J.-L.,Ieong, Nga Sze,Todd, Richard,Everson, Jack,Dove, Andrew P.
supporting information, p. 16664 - 16668 (2017/12/13)
Poly(ortho ester)s (POEs) are well-known for their surface-eroding properties and hence present unique opportunities for controlled-release and tissue-engineering applications. Their development and wide-spread investigation has, however, been severely limited by challenging synthetic requirements that incorporate unstable intermediates and are therefore highly irreproducible. Herein, the first catalytic method for the synthesis of POEs using air- and moisture-stable vinyl acetal precursors is presented. The synthesis of a range of POE structures is demonstrated, including those that are extremely difficult to achieve by other synthetic methods. Furthermore, application of this chemistry permits efficient installation of functional groups through ortho ester linkages on an aliphatic polycarbonate.
