65971-75-7

Basic information

• Product Name: 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE
• Synonyms: 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE
• CAS NO: 65971-75-7
• Molecular Formula: C₈H₃BrClNO₂
• Molecular Weight: 260.47
• Mol File: 65971-75-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.919±0.06 g/cm3(Predicted)
• PKA: 7.62±0.20(Predicted)
• CAS DataBase Reference: 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE(65971-75-7)
• EPA Substance Registry System: 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE(65971-75-7)

Safety Data

• Hazardous Substances Data: 65971-75-7(Hazardous Substances Data)

Upstream product

• 20780-72-7 4-bromoisatin 
• 823-54-1 3-bromo-4-chloroaniline 

Downstream Products

• 147150-14-9 6-Amino-2-bromo-3-chloro-benzoic acid methyl ester 
• 65971-76-8 6-amino-2-bromo-3-chlorobenzoic acid 

Relevant articles and documents

FUSED 1,4-OXAZEPINES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS

The present disclosure provides fused 1,4-oxazepines and related analogs represented by Formula (I) and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1, R2a, R2b, R3a, R3b, R4, R5, A, and Y are as defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a condition or disorder responsive to inhibition of BET bromodomains such as cancer.