659722-22-2Relevant academic research and scientific papers
Method of drug design
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, (2017/12/31)
The invention provides a method of identifying biologically active compounds comprising: (a) designing a first library of compounds of formula (1) to scan molecular diversity wherein each compound of the library has at least two pharmacophoric groups R1 t
Orthogonally protected monosaccharide building blocks for solid phase production of diversity oriented libraries
Rajaratnam, Premraj,Gupta, Praveer,Katavic, Peter,Kuipers, Krystle,Huyh, Ngoc,Ryan, Sarah,Falzun, Tania,Tometzki, Gerrald B.,Bornaghi, Laurent,Le Thanh, Giang,Abbenante, Giovanni,Liu, Ligong,Meutermans, Wim,Wimmer, Norbert,West, Michael L.
experimental part, p. 693 - 699 (2010/09/05)
The large scale synthesis of three orthogonally protected monosaccharide scaffolds suitable for use in the solid phase preparation of large diversity libraries is presented. Scaffolds based on 2-amino-2-deoxy-d-glucopyranose, 2-amino-2-deoxy-d-allopyranos
DERIVATIVES OF MONOSACCHARIDES FOR DRUG DISCOVERY
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Page 17, (2010/02/06)
New compounds and methods for the preparation of combinatorial libraries of potentially biologically active compounds are based on monosaccharides of formula (I) being a derivative of a furanose or pyranose form of a monosaccharide.
