65973-98-0 Usage
General Description
The chemical "4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-(3-nitrophenyl)-" is a compound with the molecular formula C11H8N4O3. It is a derivative of pyrazolo[3,4-d]pyrimidin-4-one, and it contains a dihydro-1-(3-nitrophenyl) group. This chemical has potential applications in pharmaceutical research and drug development due to its unique structure and properties. It may also have biological activities that make it useful for various medicinal and therapeutic purposes. Further research and study are needed to fully understand the potential uses and applications of 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-(3-nitrophenyl)-.
Check Digit Verification of cas no
The CAS Registry Mumber 65973-98-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,9,7 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 65973-98:
(7*6)+(6*5)+(5*9)+(4*7)+(3*3)+(2*9)+(1*8)=180
180 % 10 = 0
So 65973-98-0 is a valid CAS Registry Number.
65973-98-0Relevant academic research and scientific papers
Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors
Peat, Andrew J.,Boucheron, Joyce A.,Dickerson, Scott H.,Garrido, Dulce,Mills, Wendy,Peckham, Jennifer,Preugschat, Frank,Smalley, Terrence,Schweiker, Stephanie L.,Wilson, Jayme R.,Wang, Tony Y.,Zhou, Huiqiang Q.,Thomson, Stephen A.
, p. 2121 - 2125 (2007/10/03)
A series of [1-aryl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]arylhydrazones were discovered as novel inhibitors glycogen synthase kinase-3 (GSK-3). Based on initial modeling a detailed SAR was constructed. Modification of the interior binding aryl ring (Ar1) determined this to be a tight binding region with little room for modification. As predicted from the model, a large variety of modifications could be incorporated into the hydrazone aryl ring. This work led to GSK-3 inhibitors in the low nano-molar range.
PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS
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Page 31, (2010/02/06)
The present invention relates generally to inhibitors of the kinases and more particularly to novel pyrazolopyrimidine compounds.
