65973-99-1Relevant academic research and scientific papers
Heterocyclic Synthesis Using Hydrazonoyl Halides: Synthesis of Annelated Pyrimidines, Pyridazines and Pyrazoles
Abdelhamid, Abdou O.
, p. 1239 - 1262 (2007/10/02)
Aminocyanopyrazoles and dihydropyrrolopyrazole-4,6-diones were obtained in good yields by the reaction of hydrazonoyl halides with malononitrile and N-arylmaleimides respectively. Pyrazolopyrimidines and pyrazolopyridazines were synthesized in quantitative yields by the reaction of formic acid or formamide and hydrazine hydrate with aminocyanopyrazoles. Novel ring systems, 4-mercapto-1,2,3,5,6,7-hexaazaacenaphthylenes 20 and 7-thia-1,2,4,5,6,10-hexaazacyclopentacenaphthylenes 22 were prepared by the reaction of 18 with carbon disulfide and the reaction of 21 with acetic anhydride. The structures of the products were assigned and confirmed on the basis of their elemental analyses, spectral data and alternate synthesis wherever possible.
3-Chlor-5-dimethylamino-2-formyl-4-aza-2,4-pentadiennitril, Synthese und Umsetzungen mit Nucleophilen
Klemm, Kurt,Pruesse, Wolfgang,Baron, Lothar,Daltrozzo, Ewald
, p. 2001 - 2018 (2007/10/02)
3-Chloro-5-dimethylamino-2-formyl-4-aza-2,4-pentadienenitrile (7) is prepared by partial hydrolysis of the iminium perchlorate 1.In 7 the electrophilic centres (1, 3, 5) regioselectively react with secondary alkylamines, arylamines, and hydrazine derivatives to yield 3-amino-substituted formylazapentadienenitriles and (hydrazonomethyl)azapentadienenitriles.Intramolecular cyclisation leads to triazole betaines, pyrazoles, and 1,4-dihydropyrimidines.
