659748-16-0

Upstream product

• 612-41-9 2-nitrocinnamic acid 
• 659748-14-8 methyl 3-[2-(3-phenylureido)phenyl]acrylate 
• 88939-75-7 methyl (2E)-3-(2-aminophenyl)propenoate 
• 39228-29-0 (E)-methyl 2-nitrocinnamate 
• 139210-05-2 methyl 3-[2-(phenyliminomethyleneamino)phenyl]acrylate 

Downstream Products

• 741720-07-0 (2,3-diphenyl-3,4-dihydro-quinazolin-4-yl)-acetic acid 

Relevant academic research and scientific papers

Synthesis of 2-substituted 3,4-dihydroquinazoline derivatives via regioselective addition of a carbon nucleophile to a carbodiimide

Synthesis of 2-alkyl or phenyl-substituted 3,4-dihydroquinazoline derivatives (6) is described via regioselective carbon nucleophilic addition (RMgBr and RM) to a carbodiimide (4) followed by intramolecular conjugate addition.