66-38-6

Upstream product

• 4462-61-7 4,4′-sulfonyldibenzoyldichloride 
• 599-66-6 bis(4-methylphenyl) sulfone 

Downstream Products

• 3731-85-9 4.4'-Bis-(3-hydroxy-4-isopropyloxycarbonyl-phenyliminomethyl)-diphenylsulfon 
• 3525-71-1 4,4'-Bis-cyclohexyliminomethyl-diphenylsulfon 
• 4091-33-2 4,4'-Bis-(4-ethoxycarbonyl-phenyliminomethyl)-diphenylsulfon 
• 3731-82-6 4.4'-Bis-(3-hydroxy-4-methoxycarbonyl-phenyliminomethyl)-diphenylsulfon 
• 2449-35-6 bis(4-carboxyphenyl)sulfone 
• 52123-62-3 (sulfonylbis(4,1-phenylene))dimethanol 

Relevant academic research and scientific papers

24-Sulfur-substituted analogs of 1 alpha, 25-dihydroxy vitamin D3

The present invention provides novel C24-sulfone analogs of 1α,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.

24-sulfur-substituted analogs of 1alpha, 25-dihydroxy vitamin D3

The present invention provides novel C24-aryl sulfone analogs of 1α,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.