660-65-1

Basic information

• Product Name: Hexadecanoic acid16-hydroxybimol.cyclic ester ;;
• CAS NO: 660-65-1
• Molecular Weight: 508.826
• Mol File: 660-65-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Hexadecanoic acid16-hydroxybimol.cyclic ester ;;(CAS DataBase Reference)
• NIST Chemistry Reference: Hexadecanoic acid16-hydroxybimol.cyclic ester ;;(660-65-1)
• EPA Substance Registry System: Hexadecanoic acid16-hydroxybimol.cyclic ester ;;(660-65-1)

Safety Data

• Hazardous Substances Data: 660-65-1(Hazardous Substances Data)

Upstream product

• 2536-36-9 16-iodohexadecanoic acid 
• 36575-67-4 16-hydroxyhexadecanoic acid methyl ester 
• 506-13-8 16-hydroxyhexadecanoic acid 

Relevant articles and documents

A new method for the synthesis of carboxylic esters and lactones with di-2-thienyl carbonate (2-DTC) by the promotion of DMAP and iodine

The esterification of carboxylic acids with alcohols by using di-2-thienyl carbonate (2-DTC) in the presence of a catalytic amount of 4-(dimethylamino) pyridine (DMAP) proceeded smoothly to afford the corresponding esters in good-to-high yields along with 2(5H)-thiophenone. This esterification was accelerated by the addition of an equimolar amount of iodine to afford the esters in higher yields within a shorter reaction time. Further, cyclization of ω-hydroxycarboxylic acids with an equimolar amount of 2-DTC in the presence of a catalytic amount of DMAP, followed by the addition of 1-4 equimolar amounts of iodine, afforded the corresponding lactones in good-to-high yields under mild conditions. This method was successfully employed in the synthesis of erythro-aleuritic acid lactone.

A new method for the lactonization of ω-hydroxy carboxylic acids with Di-2-thienyl carbonate by the promotion of DMAP and iodine

Successive reactions of ω-hydroxycarboxylic acids with an equimolar amount of di-2-thienyl carbonate (2-DTC) in the presence of a catalytic amount of 4-(dimethylamino)pyridine (DMAP) followed by an addition of 2-4 equimolar amounts of iodine afforded the corresponding lactones in good to high yields. Copyright

A new method for the polymer-supported synthesis of cyclic oligoesters for potential applications in macrocyclic lactone synthesis and combinatorial chemistry

Attachment of ω-hydroxyalkanecarboxylic acids to Merrifield beads followed by treatment with a catalytic amount of di-n-butyltin oxide in chlorobenzene at 133 °C for 4-18 h brought about the formation of the corresponding cyclic oligomers (COs) as the mai