66000-41-7

Usage

Commonly used in synthesis of pharmaceuticals and agrochemicals

The compound has potential biological activities that make it useful in the production of drugs and pesticides.

Anti-inflammatory and antifungal properties

The compound has been studied for its ability to reduce inflammation and inhibit the growth of fungi, making it a valuable tool in drug discovery and development.

Trifluoromethyl group attached to phenyl ring

The presence of this group enhances the compound's stability and lipophilicity, making it more suitable as a drug candidate.

Versatile and important chemical in medicinal chemistry

The compound's unique properties and potential applications make it a valuable asset in the field of medicinal chemistry.

Upstream product

• 1354722-12-5 3-nitro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole 
• 401-81-0 m-trifluoromethylphenyl iodide 
• 66000-40-6 3-amino-1-<3-(trifluoromethyl)phenyl>-2-pyrazoline 
• 368-78-5 3-(trifluoromethyl)phenylhydrazine 

Downstream Products

• 104164-08-1 5-Chloromethyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one 
• 1354722-15-8 5-chloro-2-nitro-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)-benzamide 
• 1354722-19-2 2-nitro-5-(piperidin-1-yl)-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide 
• 1354722-20-5 2-amino-5-(piperidin-1-yl)-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide 
• 1354722-21-6 6-(chloromethyl)-N-(4-(piperidin-1-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)picolinamide 
• 1354722-22-7 tert-butyl 3-(2-(2-(2-(((6-((4-(piperidin-1-yl)-2-((1-(3-(trifluoromethyl)-phenyl)-1H-pyrazol-3-yI)carbamoyl)phenyl)carbamoyl)pyridin-2-yl)methyl)(methyl)-amino)ethoxy)ethoxy)ethoxy)propanoate 
• 1354721-68-8 2-(4-(((2-(diethylamino)ethyl)(methyl)amino)methyl)benzamido)-5-(piperidin-1-yl)-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide 
• 1354721-70-2 N-methyl-N-(2-morpholinoethyl)-N'-(4-(piperidin-1-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)isophthalamide 
• 1354721-71-3 2-(3-(((2-(diethylamino)ethyl)(methyl)amino)methyl)benzamido)-5-(piperidin-1-yl)-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide 
• 1354721-74-6 N-(4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)-N'-methyl-N'-(2-morpholinoethyl)isophthalamide 2,2,2-trifluoroacetate 
• 1354721-75-7 2-methyl-1-oxo-1-(3-((4-(piperidin-1-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-5,8,11-trioxa-2-azatetradecan-14-oic acid 
• 1354722-26-1 3-((4-(piperidin-1-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)benzoic acid 
• 1354722-27-2 C₄₄H₅₃F₃N₆O₈ 
• 1354721-77-9 2-(3-(((3-((2-methoxyethyl)amino)-3-oxopropyl)(methyl)amino)methyl)benzamido)-5-(piperidin-1-yl)-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT

Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac

PYRIDO[3,4-D]PYRIMIDINYL ACETAMIDE DERIVATIVES AS TRPA1 MODULATORS

Provided are pyrido[3,4-d]pyrimidinyl acetamide derivatives as Transient Receptor Potential Ankyrin (TRPA) modulators. In particular, the compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by Transient Receptor Potential Ankyrin 1 (TRPAl). Also provided herein are processes for preparing the compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1. Formula (I).