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Ethanesulfonamide, N-methyl-, also known as N-Methylethanesulfonamide or MESNA, is an organic compound with the chemical formula C3H9NO2S. It is a colorless, crystalline solid that is soluble in water and slightly soluble in ethanol. MESNA is primarily used as a chemoprotective agent in cancer treatment, particularly in combination with ifosfamide, a cytotoxic drug. It works by binding to and neutralizing the toxic metabolites produced by ifosfamide, thereby reducing the risk of hemorrhagic cystitis, a common side effect of ifosfamide therapy. MESNA is administered intravenously or orally and is rapidly metabolized in the liver. Its safety profile is generally favorable, with minimal side effects, making it an essential component in the management of patients undergoing chemotherapy with ifosfamide.

6601-37-2

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6601-37-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6601-37-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,0 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6601-37:
(6*6)+(5*6)+(4*0)+(3*1)+(2*3)+(1*7)=82
82 % 10 = 2
So 6601-37-2 is a valid CAS Registry Number.

6601-37-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-ethanesulfonamide

1.2 Other means of identification

Product number -
Other names N-Methyl-aethansulfonamid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6601-37-2 SDS

6601-37-2Relevant academic research and scientific papers

Substituent-controlled annuloselectivity and stereoselectivity in the sulfa-Staudinger cycloadditions

Yang, Zhanhui,Chen, Ning,Xu, Jiaxi

, p. 3611 - 3620 (2015/04/22)

In the sulfa-Staudinger cycloadditions of imines and sulfonyl chlorides, the annuloselectivity is mainly controlled by the electronic effect of the α-substituents of sulfonyl chlorides and the nucleophilicity of imines. Sulfonyl chlorides with weakly elec

Establishment of heterolytic and homolytic Y-NO2 bond dissociation energy scales of nitro-containing compounds in acetonitrile: Chemical origin of NO2 release and capture

Li, Xin,Zhu, Xiao-Qing,Zhang, Fan,Wang, Xiao-Xiao,Cheng, Jin-Pei

, p. 2428 - 2431 (2008/09/20)

(Chemical Equation Presented) The first heterolytic and homolytic N(O)-NO2 bond dissociation energy scales of three types Y-nitro (Y = N, O) compounds and corresponding radical anions in acetonitrile were established by using titration calorimetry combined with relevant electrochemical data through proper thermodynamic cycles.

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