66031-49-0

Upstream product

• 2396-65-8 1,8-nonadiyn 
• 1123-11-1 cyclonona-1,2-diene 
• 107175-49-5 6-hepten-1-yl iodide 
• 70277-75-7 lithium acetylide 
• 64818-37-7 hept-6-enyl methanesulfonate 
• 821-41-0 5-Hexen-1-ol 
• 5048-25-9 6-cyano-1-hexene 
• 1119-60-4 hept-6-enoic acid 
• 13175-44-5 oct-7-en-1-ol 
• 558-13-4 carbon tetrabromide 
• 21573-31-9 oct-7-enal 
• 62179-18-4 (2E)-octa-2,7-dien-1-ol 
• 4117-10-6 6-hepten-1-ol 
• 4117-09-3 7-bromo-hept-1-ene 

Downstream Products

• 1390635-59-2 C₂₄H₂₅F₃O₃ 
• 1390635-60-5 C₂₄H₂₅F₃O₃ 
• 10482-53-8 (8Z,11Z,14Z)-heptadeca-1,8,11,14-tetraene 

Relevant academic research and scientific papers

EIGHT ALIPHATIC ALDEHYDES FROM CIRSIUM DIPSACOLEPIS AND THEIR STEREOSELECTIVE SYNTHESIS

Two new and six known aliphatic aldehydes have been isolated from the roots of Cirsium dipsacolepis, viz. 7-octenal, (2E)-2,8-nonadienal, (2E)-2,9-decadienal, (2E)-2,10-undecadienal, (2E,4E)-2,4,10-undecatrienal, (2E,4E)-2,4,11-dodecatrienal, (2Z,4Z)-2,4,11-dodecatrienal and (2E,4Z)-2,4,11-dodecatrienal.The aldehydes were identified and synthesized stereoselectively from alkene-α,ο-diynes. Key word Index-- Cirsium dipsacolepis; Compositae; roots; unsaturated aliphatic aldehydes; aplotaxene; cyperene; synthesis.

Selective iron-catalyzed transfer hydrogenation of terminal alkynes

A novel iron-catalyzed transfer hydrogenation of alkynes to the corresponding alkenes applying formic acid as a hydrogen donor is reported. An in situ combination of Fe(BF4)2·6H2O and tetraphos allows for highly selective hydrogenation of a broad range of aromatic and aliphatic alkynes tolerating different functional groups.

Experimental determination of the activation parameters and stereoselectivities of the intramolecular Diels-Alder reactions of 1,3,8-nonatriene, 1,3,9-decatriene, and 1,3,10-undecatriene and transition state modeling with the Monte Carlo-Jumping between Wells/molecular dynamics method

Experimental activation parameters for the intramolecular Diels-Alder reactions of 1,3,8-nonatriene, 1,3,9-decatriene, and 1,3,10-undecatriene have been measured, and the Monte Carlo-Jumping between Wells/Stochastic Dynamics [MC(JBW)/SD] method, which gives relative free energies of activation, was tested as a means to predict stereoselectivities. The predictions are compared to experimental results, and to predictions from quantum and molecular mechanics methods.

ISOLATION AND TOTAL SYNTHESIS OF THE MAJOR CONSTITUENT OF THE ROOTS OF CENTAUREA INCANA: APLOTAXENE

The major constituent of the petroleum ether extract of the root of Centaurea incana was identified as (8Z,11Z,14Z)-1,8,11,14-heptadecatetraene (Aplotaxene 1).A convergent and highly stereoselective synthesis of this compound is reported.

THERMAL REARRANGEMENTS OF CYCLIC ALLENES via RETRO-ENE REACTIONS

Flow vacuum thermolysis (500-650 deg C) of 1,2-cyclonona- and 1,2-cyclodecadienes yields, as primary products, terminal enynes and enedienes.Secondary intramolecular Diels-Alder reactions of the enedienes afford cis and trans bicyclics.