107175-49-5Relevant academic research and scientific papers
Novel potent apoA-I peptide mimetics that stimulate cholesterol efflux and pre-β particle formation in vitro
Ingenito, Raffaele,Burton, Charlotte,Langella, Annunziata,Chen, Xun,Zytko, Karolina,Pessi, Antonello,Wang, Jun,Bianchi, Elisabetta
, p. 236 - 239 (2010)
Reverse cholesterol transport (RCT) is believed to be the primary mechanism by which HDL and its major protein apoA-I protect against atherosclerosis. Starting from the inactive 22-amino acid peptide representing the consensus sequence of the class A amphipathic helical repeats of apoA-I, we designed novel peptides able to mobilize cholesterol from macrophages in vitro, and to stimulate the formation of 'nascent HDL' particles, with potency comparable to the entire apoA-I protein.
INTRAMOLEKULARE CYCLOADDITIONEN MIT ISOBENZOFURANEN - III. EIN HYDRIERTES NAPHTHOTHIOPHEN AUS EINEM 1-ALKENYLTHIENOFURAN
Schoening, A.,Friedrichsen, W.
, p. 1137 - 1138 (2007/10/02)
The synthesis of tetrahydronaphthothiophene 6 utilizing an intramolecular Diels-Alder reaction with an 1-alkenylthienofuran 4 is described.
