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7-Bromo-3-methylbenzo[d]isoxazole, also known as Br-3-MeBenzoD-ISOX, is a heterocyclic aromatic organic compound with the molecular formula C8H5BrN2O. It features a 5-membered isoxazole ring fused to a benzene ring and is commonly utilized as a building block in the synthesis of various bioactive compounds in pharmaceuticals and agrochemicals. This chemical has also been studied for its potential neuroprotective and anti-inflammatory properties, as well as its use as a tool compound for targeting specific biological pathways. However, due to its potential hazards and toxicity, it is crucial to handle 7-Bromo-3-methylbenzo[d]isoxazole with caution and adhere to safety procedures.

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  • 66033-75-8 Structure
  • Basic information

    1. Product Name: 7-Bromo-3-methylbenzo[d]isoxazole
    2. Synonyms: 7-Bromo-3-methylbenzo[d]isoxazole
    3. CAS NO:66033-75-8
    4. Molecular Formula:
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 66033-75-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-Bromo-3-methylbenzo[d]isoxazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-Bromo-3-methylbenzo[d]isoxazole(66033-75-8)
    11. EPA Substance Registry System: 7-Bromo-3-methylbenzo[d]isoxazole(66033-75-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 66033-75-8(Hazardous Substances Data)

66033-75-8 Usage

Uses

Used in Pharmaceutical Industry:
7-Bromo-3-methylbenzo[d]isoxazole is used as a building block for synthesizing various bioactive compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 7-Bromo-3-methylbenzo[d]isoxazole serves as a key component in the synthesis of bioactive molecules, potentially leading to the creation of novel pesticides or other agrochemical products.
Used in Neuroprotective and Anti-Inflammatory Research:
7-Bromo-3-methylbenzo[d]isoxazole is used as a subject of study for its potential neuroprotective and anti-inflammatory properties, which could lead to advancements in the treatment of neurological disorders and inflammatory conditions.
Used as a Tool Compound in Biological Research:
This chemical is also utilized as a tool compound for targeting specific biological pathways, aiding researchers in understanding complex biological mechanisms and developing targeted therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 66033-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,3 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 66033-75:
(7*6)+(6*6)+(5*0)+(4*3)+(3*3)+(2*7)+(1*5)=118
118 % 10 = 8
So 66033-75-8 is a valid CAS Registry Number.

66033-75-8Downstream Products

66033-75-8Relevant articles and documents

Discovery of novel 3-{[(5,5-dimethyl-4,5-dihydroisoxazol-3-yl)sulfonyl]methyl}benzo[d]isoxazole analogs as promising very long chain fatty acids inhibitors

Lin, Jian,Li, Yitao,Hu, Xiaoyun,Chi, Weilin,Zeng, Shuiming,Xu, Junxing

, p. 226 - 240 (2020/10/19)

Very long chain fatty acids (VLCFAs) are one of the most principal and promising targets for herbicides discovery. In order to explore and find novel VLCFAs inhibitors with higher herbicidal activity and improved crop safety, a variety of new 3-{[(5,5-dimethyl-4,5-dihydroisoxazol-3-yl)sulfonyl]methyl}benzo[d]isoxazole derivatives were reasonably designed and synthesized. The results of greenhouse experiments indicated that several compounds exhibited good herbicidal activity against Digitaria sanguinalis, Echinochloa crus-galli, and Setaria faberii at rates of 150 g ai/ha. Compounds g4 and h1 displayed promising herbicidal activity against D sanguinalis and E crus-galli at rates of 75 g ai/ha, which is better than commercial pyroxasulfone and S-metolachlor. Moreover, compound h1 displayed higher activity against E crus-galli, D sanguinalis, and S faberii than pyroxasulfone and S-metolachlor even at a rate of 37.5 and 18.75 g ai/ha. Furthermore, both of the compounds g4 and h1 were much safer to these tested crops, especially to rice, wheat and rape, at the rate of 150 g ai/ha than pyroxasulfone. Therefore, h1 may act as a new lead structure for novel herbicides discovery.

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