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3-METHYL-1,2-BENZISOXAZOL-6-OL, also known as 3-methyl-1,2-benzisoxazole-6-ol, is a benzisoxazole derivative with the molecular formula C9H9NO2. It is a chemical compound that possesses unique chemical properties, making it a versatile substance for various applications in pharmaceuticals, agrochemicals, and as a potential neuroprotective agent.

66033-92-9

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66033-92-9 Usage

Uses

Used in Pharmaceutical Industry:
3-METHYL-1,2-BENZISOXAZOL-6-OL is used as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into the development of new drugs, potentially enhancing their therapeutic effects and targeting specific diseases.
Used in Agrochemical Industry:
In the agrochemical industry, 3-METHYL-1,2-BENZISOXAZOL-6-OL is utilized as a key component in the production of certain agrochemicals. Its chemical properties make it suitable for use in the development of pesticides, herbicides, and other agricultural chemicals, contributing to improved crop protection and yield.
Used as a Neuroprotective Agent:
3-METHYL-1,2-BENZISOXAZOL-6-OL has been studied for its potential as a neuroprotective agent. Its ability to protect neurons from damage and degeneration makes it a promising candidate for the development of treatments for neurodegenerative diseases such as Alzheimer's, Parkinson's, and multiple sclerosis.
Used for Antioxidant Properties:
The antioxidant properties of 3-METHYL-1,2-BENZISOXAZOL-6-OL make it beneficial for various industrial and medical applications. Its ability to neutralize free radicals and prevent oxidative stress can be harnessed in the development of products that promote health and longevity, as well as in the preservation of materials and substances prone to oxidation.

Check Digit Verification of cas no

The CAS Registry Mumber 66033-92-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,3 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 66033-92:
(7*6)+(6*6)+(5*0)+(4*3)+(3*3)+(2*9)+(1*2)=119
119 % 10 = 9
So 66033-92-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO2/c1-5-7-3-2-6(10)4-8(7)11-9-5/h2-4,10H,1H3

66033-92-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-methyl-2H-1,2-benzoxazol-6-one

1.2 Other means of identification

Product number -
Other names 3-methyl-1,2-benzoxazol-6-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66033-92-9 SDS

66033-92-9Relevant academic research and scientific papers

Benzoisoxazole compound derivative and applications thereof

-

Paragraph 0075; 0076; 0078, (2019/01/09)

The present invention provides a benzoisoxazole compound derivative and applications thereof. According to the present invention, the in vitro receptor binding assay results show that the compound hashigh affinity to H3 receptors, can be used for improvin

7H - benzisoxazole and [7, 6 - e] [1, 3] oxazine derivative and application thereof

-

, (2017/08/14)

The invention discloses 7H-benzo-isoxazole-[7,6-e][1,3]oxazine derivatives as shown in the formula I or pharmaceutically acceptable hydrates/salts thereof, and further discloses stereoisomers or tautomers of the 7H-benzo-isoxazole-[7,6-e][1,3]oxazine deri

Triflic anhydride: A mild reagent for highly efficient synthesis of 1,2-benzisoxazoles, isoxazolo, and isothiazolo quinolines without additive or base

Kalkhambkar, Rajesh G.,Yuvaraj

supporting information, p. 547 - 555 (2014/01/23)

The synthetic utility of trifluoromethanesulphonic anhydride (triflic anhydride, TA) without additive or base for the high-yielding synthesis of a wide variety of 1,2-benzisoxazoles from 2-hydroxyaryl aldoximes and ketoximes under mild conditions has been carried out for the first time. As a continuation of our study, syntheses of isoxazolo and isothiazolo quinolones have also been demonstrated using triflic anhydride under similar conditions. This method is simple and has benefits from the easy way to isolate the products in excellent yields.

5-Thioxylopyranose Compounds

-

, (2009/05/28)

5-thioxylose compounds, especially 5-thioxylopyranose compounds, a process for their preparation, and their use for treating and/or inhibiting thromboses, especially venous thromboses. The compounds correspond to formula I: in which the pentapyranosyl gro

A novel method for the highly efficient synthesis of 1,2-benzisoxazoles under neutral conditions using the Ph3P/DDQ system

Iranpoor, Nasser,Firouzabadi, Habib,Nowrouzi, Najmeh

, p. 8247 - 8250 (2007/10/03)

The use of Ph3P/DDQ offers a novel, neutral and highly efficient method for the efficient conversion of 2-hydroxyaryl aldoximes and ketoximes to 1,2-benzisoxazoles in excellent yields at room temperature.

Synthesis of New Isoxazoles from Isoxazolines, Chalkones, Chalkone Dibromides, Epoxides and Acetylated Ketoximes and Their Conversion into Novel Heterocycles

Elkasaby, M. A.,Salem, M. A. I.

, p. 571 - 575 (2007/10/02)

A convenient and easy conversion of 2-isoxazolines (II) to isoxazoles (V) via N-bromosuccinimide bromination and subsequent dehydrobromination with bases is described.The isoxazoles have also been synthesized from chalkones (I), chalkone dibromides (III)

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