66046-42-2

Usage

Uses

Used in Organic Synthesis:
[3-(4-CHLOROPHENYL)-5-ISOXAZOLYL]METHANAMINE is used as a building block for the synthesis of more complex organic molecules. Its presence in the molecular structure allows for the creation of a wide range of compounds with diverse properties and potential applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [3-(4-CHLOROPHENYL)-5-ISOXAZOLYL]METHANAMINE is used as a precursor in the development of new drugs. Its unique structure and functional groups make it an attractive starting point for the design and synthesis of novel therapeutic agents.
Used in Drug Development:
As a potential drug candidate, [3-(4-CHLOROPHENYL)-5-ISOXAZOLYL]METHANAMINE is being investigated for its potential therapeutic effects. Its unique structure and functional groups may contribute to its efficacy in treating various medical conditions, making it an interesting target for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C10H9ClN2O/c11-8-3-1-7(2-4-8)10-5-9(6-12)14-13-10/h1-5H,6,12H2

Upstream product

• 478048-78-1 C₁₈H₁₁ClN₂O₃ 
• 104-88-1 4-chlorobenzaldehyde 
• 3848-36-0 4-chlorobenzaldoxime 
• 206055-90-5 3-(4-chlorophenyl)-5-hydroxymethylisoxazole 
• 5300-92-5 5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole 
• 3717-24-6 4-chlorobenzaldehyde oxime 
• 2450-71-7 Propargylamine 
• 66046-43-3 1-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]-3,5,7-triaza-1-azoniaadamantane bromide 

Downstream Products

• 66046-39-7 3-(4-chlorophenyl)-5-isothiocyanatomethylisoxazole 
• 66046-37-5 1-methyl-3-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]-2-thiourea 
• 1240190-06-0 N-[(3-p-chlorophenylisoxazol-5-yl)-methyl]-(R)-2-tert-butoxycarbonylmethylhexanamide 
• 1240190-20-8 (R)-2-butyl-N₄-hydroxy-N₁-[(3-p-chlorophenylisoxazol-5-yl)-methyl]succinamide 
• 1240190-14-0 N-[(3-p-chlorophenylisoxazol-5-yl)-methyl]-(R)-2-methoxycarbonylmethylhexanamide 

Relevant academic research and scientific papers

Synthesis and preliminary antibacterial evaluation of 2-butyl succinate-based hydroxamate derivatives containing isoxazole rings

Two series of novel 2-butyl succinate-based Hydroxamate derivatives containing isoxazole rings were synthesized, characterized and evaluated for antibacterial activity. The synthesized compounds were found to exhibit weak to moderate inhibitory activity against Staphytlococcus aureu and Klebsiellar pneumonia in vitro. All the compounds synthesized were found to be more effective against Klebsiellar pneumonia compared to Staphytlococcus aureu.

Design, synthesis, and herbicidal activities of novel 2-cyanoacrylates containing isoxazole moieties

A series of novel 2-cyanoacrylates containing an isoxazole moiety were designed and synthesized. Their structures were characterized by 1H NMR and elemental analysis (or high-resolution mass spectrometry). Their herbicidal activities against four species were evaluated, and the results indicated that some of the title compounds showed excellent herbicidal activities against rape and amaranth pigweed in postemergence treatment even at a dose of 75 g/ha.

GLYCYRRHETINIC ACID-30-AMIDE DERIVATIVES AND THE USES THEREOF

The present invention relates to the field of a medicine for treating diseases associated with inflammation, immunity or infection, and in particular, to glycyrrhetinic acid-30-amide derivatives of general formula I and their preparation, and a pharmaceutical composition containing the same. Said derivatives and composition exhibit anti -inflammatory, analgesic, anti-allergic, cough-preventing, liver-protecting and anti-viral properties, wherein each group is as defined in the description.

Fungicidal 3-phenyl-5-(substituted methyl) isoxaxoles

A class of isoxazoles having a phenyl or substituted-phenyl group at the 3-position and a substituted-methyl group at the 5-position are useful for the control of fungal foliar phytopathogens.