66066-03-3Relevant academic research and scientific papers
Synthetic entries to substituted bicyclic pyridones
Cheng, Dachen,Croft, Laura,Abdi, Muna,Lightfoot, Andrew,Gallagher, Timothy
, p. 5175 - 5178 (2008/09/17)
(Chemical Equation Presented) The synthesis of 6,6- and 5,6-bicyclic pyridone scaffolds has been completed using (i) an intramolecular Mitsunobu reaction and/or (ii) hydrolysis of a bicyclic pyridinium salt intermediate. Regioselective functionalization o
SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
-
Page/Page column 58, (2008/06/13)
The present invention relates to pyrimidinones and pyridones and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic ? cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.
Nitrogen-containing heterocyclic ring derivatives and analgesic and anti-inflammatory compositions and methods employing them
-
, (2008/06/13)
Novel nitrogen-containing heterocyclic compounds shown by the formula STR1 wherein one of R1 and R2 represents a lower alkyl group, a phenyl group, a halophenyl group, or a lower alkoxyphenyl group and the other of them represents a
Novel fused derivatives of 2-pyridones
-
, (2008/06/13)
Novel nitrogen-containing heterocyclic compounds shown by the formula STR1 wherein one of R1 and R2 represents a lower alkyl group, a phenyl group, a halophenyl group, or a lower alkoxyphenyl group and the other of them represents a
