6607-31-4

Basic information

• Product Name: Benzoic acid, 4-[(2-methyl-1-oxo-2-propenyl)amino]-, ethyl ester
• CAS NO: 6607-31-4
• Molecular Formula: C13H15NO3
• Molecular Weight: 233.267
• Mol File: 6607-31-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[(2-methyl-1-oxo-2-propenyl)amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(2-methyl-1-oxo-2-propenyl)amino]-, ethyl ester(6607-31-4)
• EPA Substance Registry System: Benzoic acid, 4-[(2-methyl-1-oxo-2-propenyl)amino]-, ethyl ester(6607-31-4)

Safety Data

• Hazardous Substances Data: 6607-31-4(Hazardous Substances Data)

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 21851-68-3 4-[3-Chloro-2-(2-chloro-ethylsulfanyl)-2-methyl-propionylamino]-benzoic acid ethyl ester 
• 82186-60-5 3-acetoxy-2-methylthio-3-chloromethylpropanoic acid p-carboethoxyanilide 
• 1309763-25-4 ethyl 4-{3-methyl-2-oxo-5,6-di-n-propylpyridin-1(2H)-yl}benzoate 
• 1309763-13-0 ethyl 4-{3-methyl-2-oxo-5,6-diphenylpyridin-1(2H)-yl}benzoate 
• 126335-25-9 4-(3-Acetoxy-2-ethylsulfanyl-2-methyl-propionylamino)-benzoic acid ethyl ester 
• 126335-17-9 4-(3-Chloro-2-ethylsulfanyl-2-methyl-propionylamino)-benzoic acid ethyl ester 

Relevant articles and documents

A benzene-bridged divanadium complex-early transition metal catalyst for alkene alkylarylation with PhI(O2CR)2viadecarboxylation

The synthesis, structure and catalytic activity of a benzene-bridged divanadium complex were comprehensively studied. The reduction of (Nacnac)VCl2(1) (Nacnac = (2,6-iPr2C6H3NCMe)2HC) supported by β-diketiminate with potassium graphite (KC8) by employing benzene as the solvent allows access to the benzene-bridged inverted-sandwich divanadium complex (μ-η6:η6-C6H6)[V(Nacnac)]2(2a), which can catalyze alkene alkylarylation with hypervalent iodine(iii) reagents (HIRs)viadecarboxylation to generate regioselectively diverse indolinones. Furthermore, the mild nature of this reaction was amenable to a wide range of functionalities on alkenes and HIRs. Mechanistic studies revealed a relay sequence of decarboxylative radical alkylation/radical arylation/oxidative re-aromatization.

Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations

An inexpensive ruthenium catalyst enabled oxidative annulations of alkynes by acrylamides with ample scope, which allowed for the preparation of 2-pyridones employing various electron-rich and electron-deficient acrylamides as well as (di)aryl- and (di)alkyl-substituted alkynes.

Photochemical reactions of N-(2-halogenoalkanoyl) derivatives of anilines

The photochemical reactions of 2-substituted N-(2-halogenoalkanoyl) derivatives 1 of anilines and 5 of cyclic amines are described. Under irradiation, 2-bromo-2-methylpropananilides 1a-e undergo exclusively dehydrobromination to give N-aryl-2-methylprop-2-enamides (= methacrylanilides) 3a-e (Scheme 1 and Table 1). On irradiation of N-alkyl- and N-phenyl-substituted 2-bromo-2-methylpropananilides 1f-m, cyclization products, i.e. 1,3-dihydro-2H-indol-2-ones (= oxindoles) 2f-m and 3,4- dihydroquinolin-2(1H)-ones (= dihydrocarbostyrils) 4f-m, are obtained, besides 3f-m. On the other hand, irradiation of N-methyl-substituted 2- chloro-2-phenylacetanilides 1o-q and 2-chloroacetanilide 1r gives oxindoles 2o-r as the sole product, but in low yields (Scheme 3 and Table 2). The photocyclization of the corresponding N-phenyl derivatives 1s-v to oxindoles 2s-v proceeds smoothly. A plausible mechanism for the formation of the photoproducts is proposed (Scheme 4). Irradiation of N-(2-halogenoalkanoyl) derivatives of cyclic amines 5a-c yields the cyclization products, i.e. five- membered lactams 6a, b, and/or dehydrohalogenation products 7a,c and their cyclization products 8a,c, depending on the ring size of the amines (Scheme 5 and Table 3).