660862-46-4 Usage
General Description
2-Piperazineethanol, (2R)-(9CI) is a chemical compound with the molecular formula C6H14N2O. It is a chiral compound, meaning it has a specific spatial arrangement of atoms. This chemical is commonly used as a reactant in the synthesis of pharmaceutical compounds, particularly in the production of antihistamines and antipsychotic drugs. It is also used as a building block in the preparation of various organic compounds. Additionally, 2-Piperazineethanol, (2R)-(9CI) has potential applications in the field of medicinal chemistry and drug discovery due to its pharmacological properties. Its unique structure and reactivity make it a valuable tool for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 660862-46-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,0,8,6 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 660862-46:
(8*6)+(7*6)+(6*0)+(5*8)+(4*6)+(3*2)+(2*4)+(1*6)=174
174 % 10 = 4
So 660862-46-4 is a valid CAS Registry Number.
660862-46-4Relevant articles and documents
A Versatile Synthesis of Vinyl-Substituted Heterocycles via Regio- And Enantioselective Pd-Catalyzed Tandem Allylic Substitution
Qian, Chao,Tang, Wenjun,Tang, Wenjun
supporting information, p. 4483 - 4488 (2020/06/05)
We herein report a versatile, regio- and enantioselective palladium-catalyzed tandem allylic substitution powered by a chiral bisphosphorus ligand WingPhos with the palladium loading as low as 0.1 mol %, forming a series of chiral vinyl-substituted heterocycles, including tetrahydroquinoxalines, piperazines, dihydro-2H-benzo[b][1,4]-oxazines, and morpholines, in exellent ee's and yields. The protocol features readily available starting materials, mild reaction conditions, and a broad substrate scope. Mechanistic investigation supports a tandem allylic substitution process.
NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
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Page/Page column 15, (2010/02/12)
Acetylcholine receptor ligands of formula (I), wherein D, Ar1, E and Ar2 are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for usi
