66087-53-4

Upstream product

• 609-67-6 2-Iodobenzoyl chloride 
• 87-62-7 2,6-dimethylaniline 
• 88-67-5 2-Iodobenzoic acid 

Downstream Products

• 1788-92-7 2-methyl-3-(2,6-dimethylphenyl)quinazolin-4(3H)-one 
• 383396-53-0 3-(2,6-dimethylphenyl)-2-phenylquinazolin-4(3H)-one 
• 1616629-21-0 3-(2,6-dimethylphenyl)-2-(4-oxopentyl)quinazolin-4(3H)-one 
• 4322-76-3 2-(2,6-dimethylphenyl)benzo[d]isothiazol-3(2H)-one 
• 115819-34-6 2-azido-N-(2,6-dimethylphenyl)benzamide 

Relevant academic research and scientific papers

Syntheses of quinazolinones from 2-iodobenzamides and enaminones via copper-catalyzed domino reactions

N-Substituted 2-iodobenzamides and enaminones undergo cascade transformations to achieve quinazolinones via a copper-catalyzed Ullmann-type coupling, a Michael addition and a retro-Mannich reaction. A unique stereochemical feature of this domino process was that Z-enaminones reacted without external ligands, whereas E-enaminones required the assistance of ligands. This journal is