66087-55-6

Basic information

• Product Name: Benzamide, 2-bromo-N-methyl-N-(4-methylphenyl)-
• CAS NO: 66087-55-6
• Molecular Formula: C15H14BrNO
• Molecular Weight: 304.186
• Mol File: 66087-55-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-bromo-N-methyl-N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-bromo-N-methyl-N-(4-methylphenyl)-(66087-55-6)
• EPA Substance Registry System: Benzamide, 2-bromo-N-methyl-N-(4-methylphenyl)-(66087-55-6)

Safety Data

• Hazardous Substances Data: 66087-55-6(Hazardous Substances Data)

Upstream product

• 136926-09-5 2-bromo-N-(4-methylphenyl)benzamide 
• 74-88-4 methyl iodide 
• 106-49-0 p-toluidine 
• 88-65-3 2-bromobenzoic-acid 

Relevant articles and documents

Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors

5-Methylphenanthridium derivatives were designed, synthesized and evaluated for their in vitro antibacterial activity and cell division inhibitory activity against various Gram-positive and -negative bacteria. Among them, compounds 5A2, 5B1, 5B2, 5B3, 5C1 and 5C2 displayed the best on-target antibacterial activity with an MIC value of 4?μg/mL against B. subtilis ATCC9372 and S. pyogenes PS, showing over 2-fold better activity than sanguinarine. The SARs showed that the 5-methylphenanthridium derivatives with the alkyl side chains at the 2-postion, especially the straight alkyl side chains exerted better on-target antibacterial activity.