66089-98-3

Basic information

• Product Name: 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE
• Synonyms: OTAVA-BB BB7020410040;4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE
• CAS NO: 66089-98-3
• Molecular Formula: C₁₁H₁₃ClO₂
• Molecular Weight: 212.67
• Mol File: 66089-98-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 298.6°Cat760mmHg
• Flash Point: 113.6°C
• Appearance: /
• Density: 1.144g/cm³
• Vapor Pressure: 0.00223mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE(66089-98-3)
• EPA Substance Registry System: 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE(66089-98-3)

Safety Data

• Hazardous Substances Data: 66089-98-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13ClO2/c1-11(9-5-3-2-4-6-9)13-8-10(7-12)14-11/h2-6,10H,7-8H2,1H3

Upstream product

• 98-86-2 acetophenone 
• 106-89-8 epichlorohydrin 
• 96-24-2 3-monochloro-1,2-propanediol 

Downstream Products

• 791595-47-6 N-[(2-methyl-2-phenyl-1,3-dioxolan-4-yl)methyl]ethane-1,2-diamine 
• 98-86-2 acetophenone 
• 96-24-2 3-monochloro-1,2-propanediol 
• 66090-05-9 2-methyl-4-methylene-2-phenyl-[1,3]dioxolane 

Relevant articles and documents

WATER- OR ACID-TRIGGERED FRAGRANCE RELEASE FUNCTIONAL MONOMER AND POLYMER SYSTEM

A triggerable composition for one-stage, controlled release of a functional chemical includes a functional monomer having a structure selected from the group described herein, wherein R is a polymerizable portion, N+X- is a quaternar

The synthesis and spectral characterization of N,N-bis(2-{[(2-methyl-2- phenyl-1,3-dioxolan-4-yl)methyl] amino}ethyl)N′N′- dihydroxyethanediimidamide and its complexes

N,N-Bis(2-{[(2-methyl-2-phenyl-1,3-dioxolan-4-yl)methyl]amino}ethyl) N′,N′-dihydr oxyethanediimidamide (LH2) has been synthesized and its mononuclear complexes with Co2+, Ni2+, Cu2+, Zn2+ and Cd2

1,3-Dioxolane-based ligands as a novel class of α1-adrenoceptor antagonists

1,3-Dioxolane-based compounds (2-14) were synthesized, and the pharmacological profiles at α1-adrenoceptor subtypes were assessed by functional experiments in isolated rat vas deferens (α1A), spleen (α1B), and aorta (α1D). Compound 9, with a pA2 of 7.53, 7.36, and 8.65 at α1A, α1B, and α1D, respectively, is the most potent antagonist of the series, while compound 10 with a pA2 of 8.37 at α1D subtype and selectivity ratios of 162 (α1D/α1A) and 324 (α1D/α1B) is the most selective. Binding assays in CHO cell membranes expressing human cloned α1-adrenoceptor subtypes confirm the pharmacological profiles derived from functional experiments, although the selectivity values are somewhat lower. Therefore, it is concluded that 1,3-dioxolane-based ligands are a new class of α1-adrenoceptor antagonists.