66101-22-2Relevant academic research and scientific papers
Synthesis of (+/-)-6β-Prostaglandin I1 and (+/-)-6β-Decarboxyprostaglandin I1
Finch, Mark A. W.,Roberts, Stanley M.,Newton, Roger F.
, p. 1312 - 1316 (1981)
The known hydroxy-aldehyde (5) has been converted into 6β-decarboxyprostaglandin I1 (19) and 6β-prostaglandin I1 (3) by (i) reaction with an appropriate organometallic reagent, (ii) cyclisation via the intermediate formation of an iodonium ion, and (iii) hydrodeiodination and desilylation.
Total Synthesis of (+/-)-6β-Prostaglandin I1
Finch, Mark A. W.,Roberts, Stanley M.,Newton, Roger F.
, p. 589 - 590 (2007/10/02)
(+/-)-6β-Prostaglandin I1 (3) has been prepared from the readily available unsaturated aldehyde (6) in four steps.
