66127-00-2

Basic information

• Product Name: 3,5,6,8-TETRABROMO-[1,10]PHENANTHROLINE
• Synonyms: 3,5,6,8-TETRABROMO-[1,10]PHENANTHROLINE;3,5,6,8-TetrabroMo-1,10-phenanthroline,98%;3,5,6,8-Tetrabromo-1,10-phenanthroline 95%
• CAS NO: 66127-00-2
• Molecular Formula: C₁₂H₄Br₄N₂
• Molecular Weight: 495.79
• Product Categories: organic amine;Achiral Nitrogen
• Mol File: 66127-00-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 356°C(lit.)
• Boiling Point: 523.2±45.0 °C(Predicted)
• Appearance: white/Powder
• Density: 2.373±0.06 g/cm3(Predicted)
• PKA: 2.21±0.10(Predicted)
• CAS DataBase Reference: 3,5,6,8-TETRABROMO-[1,10]PHENANTHROLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5,6,8-TETRABROMO-[1,10]PHENANTHROLINE(66127-00-2)
• EPA Substance Registry System: 3,5,6,8-TETRABROMO-[1,10]PHENANTHROLINE(66127-00-2)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• WGK Germany: 2
• Hazardous Substances Data: 66127-00-2(Hazardous Substances Data)

Usage

Uses

3,5,6,8-Tetrabromo-1,10-phenanthroline can be used in the nickel-catalyzed amination of aryl and heteroaryl chlorides.

Upstream product

• 860193-85-7 3,5,6-tribromo-[8]quinolylamine 
• 408529-03-3 3,3-diacetoxy-2-bromo-propene 
• 66-71-7 1,10-Phenanthroline 
• 75293-96-8 acetic acid-(4,5-dibromo-2-nitro-anilide) 
• 24108-97-2 3,4-dibromoacetanilide 
• 651733-22-1 3,5,6-tribromo-8-nitro-quinoline 

Downstream Products

• 804565-42-2 ZnCl₂(N₂C₁₂H₄(C₂C₆H₅)4) 
• 1086033-76-2 3,5,6,8-tetra(4-tert-butylphenyl)-1,10-phenanthroline 
• 1086033-74-0 3,5,6,8-tetra(para-biphenyl)-1,10-phenanthroline 
• 1086033-72-8 3,5,6,8-tetraphenyl-1,10-phenanthroline 

Relevant articles and documents

Regioselective functionalization of tetrabromophenanthroline-ruthenium complexes

Structural, photophysical and photochemical characterization and reactivity of a novel polypyridyl ruthenium complex based on 3,5,6,8- tetrabromophenanthroline are discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

An efficient silane-promoted nickel-catalyzed amination of aryl and heteroaryl chlorides

(Chemical Equation Presented) A new silane-promoted nickel-catalyzed amination of aryl chlorides with 0.5 mol % of Ni(acac)2, 1 mol % of 3,5,6,8-tetrabromo-1,10-phenanthroline, and polymethylhydrosiloxane was developed. A broad range of aryl and heteroaryl chlorides can be coupled with secondary amines and anilines to give the desired (het)arylamines in good to excellent yields. The reaction is sensitive to the nature and amount of the silane promoter.