661457-48-3

Basic information

• Product Name: Carbamic acid, [(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-, phenylmethyl ester
• CAS NO: 661457-48-3
• Molecular Formula: C17H19NO3
• Molecular Weight: 285.343
• Mol File: 661457-48-3.mol

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-, phenylmethyl ester(661457-48-3)
• EPA Substance Registry System: Carbamic acid, [(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-, phenylmethyl ester(661457-48-3)

Safety Data

• Hazardous Substances Data: 661457-48-3(Hazardous Substances Data)

Upstream product

• 37577-28-9 (1S,2R)-(+)-norphedrine 
• 501-53-1 benzyl chloroformate 

Relevant articles and documents

Synthesis of N-vinyloxazolidinones and morpholines from amino alcohols and vinylsulfonium salts: Analysis of the outcome's dependence on the N-protecting group by nanospray mass spectrometry

The effect of the nature of the N-protecting group on 1,2-amino alcohols in annulation reactions with diphenylvinylsulfonium triflate has been investigated. Although tosyl and sulfinamide groups give morpholines in high yields, the use of N-Cbz leads to a high-yielding synthesis of N-vinyloxazolidinones. The reactions were monitored by nanospray MS/MS, which revealed why reactions are successful and the fate of reactive intermediates in the unsuccessful reactions.