66162-78-5Relevant academic research and scientific papers
New Total Synthesis of (+)-N-Methylanisomycin by Anodic Cyclization of δ-Alkenylamine
Tokuda, Masao,Fujita, Hirotake,Miyamoto, Tohru,Suginome, Hiroshi
, p. 2413 - 2426 (2007/10/02)
A chiral total synthesis of (+)-N-methylanisomycin (1a) from L-diethyl tartrate via 15 steps is reported.The key step in the synthesis was a regio- and stereoselective cyclization of (E)-δ-alkenylamine 12a or its (Z)-isomer 12b by anodic oxidation of thei
2-(Nuclearly-substituted)benzylpyrrolidines
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, (2015/02/20)
2-Benzylpyrrolidines bearing from 1 to 4 nuclear substituents on the benzyl ring are pharmacologically active, particularly on the CNS, on blood pressure and on pain sensation for warm-blooded animals. They are synthesized, e.g., by reducing appropriate 2-benzylpyrrolidines and are formulated into medicament compositions according to established conventional techniques.
