66179-98-4Relevant academic research and scientific papers
Synthesis of 2-(aminoacetylamino)thiazole derivatives and comparison of their local anaesthetic activity by the method of action potential
Geronikaki,Theophilidis
, p. 709 - 716 (2007/10/02)
Some numbers of the family of 2-(aminoacetylamino)thiazoles were synthesized. The structure of these compounds was identified both by elemental as well as by spectroscopic analysis (UV, IR, H-NMR, MS). The possible local anaesthetic action of these compounds was also tested using the sciatic nerve of the frog. None of the tested compounds were found to have local anaesthetic action on in vitro preparations as lidocaine, but one of the compounds showed a similar anaesthetic action to procaine.
