6618-82-2

Basic information

• Product Name: [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl]methyl dihydrogen phosphate
• Synonyms: 6453-60-7; 1-[(4aR,6R,7aS)-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 6618-82-2
• Molecular Formula: C₁₀H₁₃N₂O₇P
• Molecular Weight: 304.1932
• Mol File: 6618-82-2.mol
• Article Data: 3

Chemical Properties

• Density: 1.66g/cm³
• Refractive Index: 1.605
• CAS DataBase Reference: [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl]methyl dihydrogen phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl]methyl dihydrogen phosphate(6618-82-2)
• EPA Substance Registry System: [(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl]methyl dihydrogen phosphate(6618-82-2)

Safety Data

• Hazardous Substances Data: 6618-82-2(Hazardous Substances Data)

Upstream product

• 365-07-1 thymidine 5'-phosphate 
• 538-75-0 dicyclohexyl-carbodiimide 

Relevant articles and documents

Novel Approach to the Synthesis of Isotopomeric MonoalkylPhosphates. The Stereospecific One-pot Conversion of (Rp)-Thymidine 3'-(Nitrophenyl)-phosphorothioate into (Rp)-3'-ThymidinePhosphate

Reaction of the (Rp)-diastereoisomer of thymidine 3'-(4-nitrophenyl)phosphorothioate with styrene oxide in a medium containing water gives (Rp)-thymidine phosphate in 70percent yield with diastereoisotopomeric purity not lower than 92percent.

Synthesis of oligodesoxynucleotides with phosphoric acid triester

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