66180-32-3Relevant academic research and scientific papers
Fluorinated β-diketo phosphorus ylides: Their cyclocondensation with amidines affording 4-trifluoromethyl- And 4-perfluoroalkyl-substituted pyrimidines
Saijo, Ryosuke,Watanabe, Genki,Kurihara, Ken-Ichi,Kawase, Masami
, p. 2334 - 2345 (2014/12/10)
A study is presented for the syntheses of a series of 4-trifluoromethyl- and 4-perfluoroalkyl-substituted pyrimidines from the reaction of trifluoromethyl or perfluoroalkyl β-diketo phosphorus ylides (Ph3P=C(CORF)COR) with amidine hydrochloride.
Regiospecific O-alkylation of 4-polyfluoroalkyl-1H-pyrimidin-2-ones
Khudina,Ivanova,Burgart,Kodess,Saloutin
experimental part, p. 901 - 905 (2012/02/05)
The alkylation of 4-polyfluoroalkylpyrimidin-2-ones with iodomethane, 4-bromobutyl acetate, and epichlorhydrin occurs regiospecifically to form O-regioisomers.
