6619-28-9

Basic information

• Product Name: 1-Propanone, 1-(2-hydroxyphenyl)-3-(4-Methylphenyl)-
• Synonyms: 1-Propanone, 1-(2-hydroxyphenyl)-3-(4-Methylphenyl)-
• CAS NO: 6619-28-9
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240
• Mol File: 6619-28-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Propanone, 1-(2-hydroxyphenyl)-3-(4-Methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(2-hydroxyphenyl)-3-(4-Methylphenyl)-(6619-28-9)
• EPA Substance Registry System: 1-Propanone, 1-(2-hydroxyphenyl)-3-(4-Methylphenyl)-(6619-28-9)

Safety Data

• Hazardous Substances Data: 6619-28-9(Hazardous Substances Data)

Usage

Structure

A ketone with a hydroxyphenyl and a methylphenyl group attached to the carbon chain

Usage

Organic synthesis, fragrance ingredient in perfumes and personal care products, production of pharmaceuticals and agricultural chemicals

Industries

Versatile and valuable chemical used in various industries

Upstream product

• 6619-24-5 4-hydroxy-3-<(4-methylphenyl)methyl>-2H-1-benzopyran-2-one 
• 589-18-4 4-Methylbenzyl alcohol 
• 118-93-4 o-hydroxyacetophenone 
• 34000-27-6 1-(2-hydroxyphenyl)-3-(4-methylphenyl)prop-2-en-1-one 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 86383-68-8 C₂₂H₂₉NO₃ 
• 1443143-95-0 C₁₉H₂₀O₃ 

Relevant articles and documents

Synthesis and structural characterization of facile ruthenium(II) hydrazone complexes: Efficient catalysts in α-alkylation of ketones with primary alcohols via hydrogen auto transfer

As a immersion for development of new complexes, new Ru(II) complexes (1–3) supported by benzothiazole hydrazine Schiff bases of the type [Ru(SAL-HBT)(CO)(AsPh3)2], [Ru(VAN-HBT)(CO)(AsPh3)2] and [Ru(NAP-HBT)(CO)Cl(AsPh3)2] [SAL-HBT = (salicyl((2-(benzothiazol-2yl)hydrazono)methylphenol)), VAN-HBT = 2-((2-(benzothiazol-2-yl)hydrazono)methyl)-6 methoxyphenol) and NAP-HBT = naphtyl-2-((2-(benzothiazol-2-yl)hydrazono)methyl phenol)] were synthesized. Their identities have been established by satisfactory elemental analyses, various spectroscopic techniques (IR, (1H, 13C) NMR) and also mass spectrometry. The ruthenium(II) ion exhibits a hexa coordination with distorted octahedral geometry. In complexes 1 and 2, the ligand coordinated as dianionic tridentate fashion by forming N^N donor five member and N^O donor six member chelate rings. However, in complex 3, the ligand coordinated as monoanionic bidentate fashion by forming N^N donor five-membered ring. The new ruthenium(II) carbonyl complexes were successfully applied as catalysts in α -alkylation of aliphatic and aromatic ketones with alcohols via borrowing hydrogen strategy. Various parameters such as base, solvent, temperature, time and catalyst loading on the catalytic activity were analyzed. From the results, the catalyst 1 was found to be the best catalyst for α-alkylation reaction to obtain excellent yield. The catalytic system has a broad substrate scope, which allows the synthesis of α-alkylated ketones in mild reaction conditions with low catalyst loading under air atmosphere.

Synthesis, anticancer, structural, and computational docking studies of 3-benzylchroman-4-one derivatives

A series of 3-Benzylchroman-4-ones were synthesized and screened for anticancer activity by MTT assay. The compounds were evaluated against two cancerous cell lines BT549 (human breast carcinoma), HeLa (human cervical carcinoma), and one noncancerous cell