66200-70-2Relevant academic research and scientific papers
Nouvelles voies d'acces a des aryl-4 thienopyridines et a des aryl-7 thienopyridines
Maffrand, Jean-Pierre,Biogegrain, Robert,Courregelongue, Jean,Ferrand, Gerard,Frehel, Daniel
, p. 727 - 734 (2007/10/02)
4-Arylthienopyridines and 7-arylthienopyridines have been prepared by heating in polyphosphoric acid 2-(2-thenylamino)-1-arylethanols or propanols and 2-(3-thenylamino)-1-arylethanols and propanols, respectively.Under the Beckmann rearrangement conditions, oximes of 4-aryl-4,5-dihydro-6H-cyclopentathiophen-6-one lead to 4-aryl-4,5-dihydro-6H-thienopyridin-7-one.
Thieno [2,3-c] and [3,2-c] pyridines
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, (2008/06/13)
This invention relates to pyridine derivatives of the formulae: STR1 in which R1 is hydrogen, lower alkyl, aralkyl optionally substituted on the aromatic nucleus with at least a halogen atom or a hydroxy, nitro, amino, cyano, carboxy, alkoxycarbonyl, lower alkyl, lower alkoxy or trifluoromethyl group; R2 is hydrogen or lower alkyl; and R3 is hydrogen or at least a substituent selected from a halogen atom, a hydroxy, lower alkyl and lower alkoxy group, and their pharmaceutically acceptable inorganic or organic acid addition salts. Said compounds have particularly an anti-inflammatory and blood-platelet aggregation inhibiting activity.
