66202-12-8

Upstream product

• 73992-33-3 2-<(1-cyclohepten-3-yl)thio>acetaldehyde 
• 622-30-0 N-benzyl hydroxylalmine 
• 66202-10-6 3-(2,2-diethoxyethylthio)-1-cycloheptene 
• 68280-89-7 3-acetylmercaptocycloheptene 
• 36291-49-3 3-bromocycloheptene 

Downstream Products

• 66202-13-9 2,3β,3aβ,5,6,7,8,8aβ-octahydro-3α-benzylamino-4H-cycloheptathiophen-4α-ol 
• 73992-10-6 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4-hydroxyimino-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 1α-oxide 
• 73992-19-5 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4-hydroxyimino-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 
• 73992-19-5 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4-hydroxyimino-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 
• 73992-15-1 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4α-methoxycarbonyl-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 
• 73992-11-7 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4-oxo-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 1α-oxide 
• 73992-16-2 benzyl<2,3β,3aβ,5,6,7,8,8aβ-octahydro-4-oxo-4H-cycloheptathiophen-3α-yl>carbamic acid methyl ester 
• 73992-14-0 2,3β,3aβ,5,6,7,8,8aβ-octahydro-3α-benzylcarbomethoxyamino-4H-cycloheptathiophen-4α-ol 
• 73992-20-8 decahydro-3-benzyl-3aβ,5aβ,9aβ,9bβ-2H-thieno<3,4,5-de>cyclohepta<1,3>oxazin-2-one 

Relevant academic research and scientific papers

Olefinic Nitrone and Nitrile Oxide Cycloadditions. A Short Stereospecific Synthesis of Biotin from Cycloheptene

A novel synthesis of biotine (6) from cycloheptene (4) via the key amino alcohol 5 is described.The synthetic scheme is based upon an intramolecular nitrone-olefin cycloaddition of the reactive intermediate 13, generated in situ from the aldehyde

Synthesis of biotin

A novel process for the preparation of biotin is disclosed wherein said process employs inexpensive starting materials and reagents resulting in the obtention of biotin devoid of the biologically inactive stereoisomers.