66203-08-5 Usage
Chemical class
Benzofuran
Structure
Benzofuran ring
Cyclohexylaminoethoxy group
Methylurea group
Pharmacological activities
Diverse, not extensively studied
Potential applications
Medicinal chemistry and drug development
Presence of urea group
May contribute to pharmacological activity
Presence of benzofuran ring
Known for diverse pharmacological activities
Presence of cyclohexylaminoethoxy group
Suggests potential interactions with biological targets
Fields of interest
Pharmacology and biochemistry
Further investigation
Recommended for potential applications in drug development and understanding of biological interactions
Check Digit Verification of cas no
The CAS Registry Mumber 66203-08-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,0 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 66203-08:
(7*6)+(6*6)+(5*2)+(4*0)+(3*3)+(2*0)+(1*8)=105
105 % 10 = 5
So 66203-08-5 is a valid CAS Registry Number.
66203-08-5Relevant academic research and scientific papers
Synthesis and Antiarrhythmic Activity of New Benzofuran Derivatives
Bourgery, Guy,Dostert, Philippe,Lacour, Alain,Langlois, Michel,Pourrias, Bernard,Tisne-Versailles, Jacky
, p. 159 - 167 (2007/10/02)
Various 5-aminobenzofuran derivatives were prepared from khellin and screened intravenously in the dog for their potential antiarrhythmic activity against ouabain-induced ventricular arrhythmia and in the Harris test.From systematic structural variations it was found that two methoxy groups in positions 4 and 7 on the benzofuran ring, a tertiary aminoethoxy side chain in position 6, and a N-methylurea group in position 5 led to the most active compounds.These were then tested orally in the Harris test in the dog.The two long-acting derivativesN--N'-methylurea (8j) and N--N'-methylurea (8m) showed advantages when compared to quinidine and diisopyramide and have been selected for further studies.
