66209-39-0Relevant articles and documents
Chemospecific Cyclizations of α-Carbonyl Sulfoxonium Ylides on Aryls and Heteroaryls
Clare, Daniel,Dobson, Benjamin C.,Inglesby, Phillip A.,A?ssa, Christophe
supporting information, p. 16198 - 16202 (2019/11/03)
The functionalization of aryl and heteroaryls using α-carbonyl sulfoxonium ylides without the help of a directing group has remained so far a neglected area, despite the advantageous safety profile of sulfoxonium ylides. Described herein are the cyclizations of α-carbonyl sulfoxonium ylides onto benzenes, benzofurans and N-p-toluenesulfonyl indoles in the presence of a base in HFIP, whereas pyrroles and N-methyl indoles undergo cyclization in the presence of an iridium catalyst. Significantly, these two sets of conditions are chemospecific for each groups of substrates.
OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS
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Page/Page column 30; 41; 42, (2015/01/16)
The present invention disclose a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of benzo fused olefins of formula (II) to obtain library of dioxolo compounds of formula (I). The invention further disclsoe a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of stilbene and its derivatives of formula (III) thereof. Also disclosed herein is Wacker-type oxidation of benzo-fused olefins of formula (X). The invention further disclose compounds of formula (I) which can be useful for the treatment of HIV, cancer or malaria.
Molecular Clefts. 1. Synthetic Methodology for the Preparation of Analogues of Kagan's Ether
Harmata, Michael,Murray, Thomas
, p. 3761 - 3763 (2007/10/02)
A synthesis of analogues of Kagan's ether 7a is reported.The procedure has reasonable generality and promises to be important in the synthesis of molecular clefts.The final step consists of an electrophilic attack of an oxonium ion on an aromatic ring, an
