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• 112-26-5 1,2-bis(2-chloroethoxy)ethane 

Relevant academic research and scientific papers

1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane synthesis method

The invention discloses a 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane synthesis method which includes the steps: (1) adding 2,6-dimethoxyphenol and 1,2-(dichloroethane) ethane into ethanol-water under stirring at the temperature ranging from 20 DEG C to 30 DEG C, adding potassium hydroxide, performing reaction at the temperature ranging from 85 DEG C to 95 DEG C for 40-55 hours and performing extraction with dichloromethane to obtain extraction liquid; (2) washing the extraction liquid with 1M sodium hydroxide solution for 2-3 times, washing the extraction liquid with saturated sodium chloride solution for 2-3 times, drying anhydrous magnesium sulfate and steaming out the dichloromethane under normal pressure to obtain yellow oily liquid; (3) adding diethyl ether into the yellow oily liquid, heating the yellow oily liquid to reach the temperature ranging from 30 DEG C to 35 DEG C, filtering out insoluble substances, cooling the yellow oily liquid to the temperature ranging from -15 DEG C to -10 DEG C for 6-12 hours, and filtering the solution to obtain white powder solid 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane. The molar ratio of the 1,2-(dichloroethane) ethane, the 2,6-dimethoxyphenol to the potassium hydroxide is 1:(2-2.3):(2.2-2.5), and the volume ratio of ethanol to water is 1:(0.8-1.2). The synthesis method is mainly used for synthesizing the 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane.

Preparation method of 1,2-bis(2-(2,6- dimethoxy phenoxyl) ethyoxyl) ethane

The invention discloses a preparation method of 1,2-bis(2-(2,6- dimethoxy phenoxyl) ethyoxyl) ethane. The preparation method comprises the following steps: (1) adding a solvent and potassium hydroxide in 2,6-dimethoxyphenol and 1,2-(dichloride ethyl) ethane at the temperature of 20-30 DEG C, reacting for 36-50 hours at the temperature of 150-190 DEG C, and steaming to obtain the solvent for next reaction to obtain brown liquid, wherein the solvent is dimethyl sulfoxide or N,N-dimethylformamide, and the mole ratio of the 1,2-( dichloride ethyl) ethane, the 2,6-dimethoxyphenol and the potassium hydroxide is 1: 2-2.3: 2.2-2.5; (2) adding dichloromethane in the brown liquid, washing for 3-4 times with 1M sodium hydroxide, washing 1-2 times with sodium chloride, drying with magnesium sulfate, and steaming the dichloromethane to obtain yellow oily liquid; and (3) adding diethyl ether in the oily liquid, heating to the temperature of 30-35 DEG C, filtering out undissolved substance, cooling to the temperature of minus 15 DEG C-minus 10 DEG C for 36-48 hours, and filtering to obtain the 1,2-bis(2-(2,6- dimethoxy phenoxyl) ethyoxyl) ethane. The preparation method is used for preparing the 1,2-bis(2-(2,6- dimethoxy phenoxyl) ethyoxyl) ethane.

1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane synthesis method

The present invention discloses a 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane synthesis method, which comprises: (1) stirring at a temperature of 20 DEG C, adding 2,6-dimethoxyphenol and 1,2-(dichloroethane)ethane to acetonitrile, adding potassium hydroxide, carrying a reaction for 90 h at a temperature of 82 DEG C, and evaporating out the acetonitrile to obtain an orange turbid liquid 1; (2) adding dichloromethane to the orange turbid liquid 1, filtering, washing 6 times with 1 M sodium hydroxide, washing twice with saturated sodium chloride, drying with anhydrous magnesium sulfate, and evaporating out the dichloromethane to obtain a yellow oily liquid 2; and (3) adding ether to the yellow oily liquid 2, heating to a temperature of 35 DEG C, filtering out the insoluble matter, cooling to a temperature of 15 DEG C, cooling for 3 h, taking the upper layer solution, cooling to a temperature of 15 DEG C, cooling for 48 h, and filtering to obtain white powder solid 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane. The synthesis method of the present invention is mainly used for the synthesis of 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane.