66223-98-1

Basic information

• Product Name: 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane
• Synonyms: 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane
• CAS NO: 66223-98-1
• Molecular Weight: 422.475
• Mol File: 66223-98-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane(66223-98-1)
• EPA Substance Registry System: 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane(66223-98-1)

Safety Data

• Hazardous Substances Data: 66223-98-1(Hazardous Substances Data)

Upstream product

• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 112-26-5 1,2-bis(2-chloroethoxy)ethane 
• 31255-10-4 1,2-bis-(2-bromo-ethoxy)-ethane 

Relevant articles and documents

1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane synthesis method

The invention discloses a 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane synthesis method which includes the steps: (1) adding 2,6-dimethoxyphenol and 1,2-(dichloroethane) ethane into ethanol-water under stirring at the temperature ranging from 20 DEG C to 30 DEG C, adding potassium hydroxide, performing reaction at the temperature ranging from 85 DEG C to 95 DEG C for 40-55 hours and performing extraction with dichloromethane to obtain extraction liquid; (2) washing the extraction liquid with 1M sodium hydroxide solution for 2-3 times, washing the extraction liquid with saturated sodium chloride solution for 2-3 times, drying anhydrous magnesium sulfate and steaming out the dichloromethane under normal pressure to obtain yellow oily liquid; (3) adding diethyl ether into the yellow oily liquid, heating the yellow oily liquid to reach the temperature ranging from 30 DEG C to 35 DEG C, filtering out insoluble substances, cooling the yellow oily liquid to the temperature ranging from -15 DEG C to -10 DEG C for 6-12 hours, and filtering the solution to obtain white powder solid 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane. The molar ratio of the 1,2-(dichloroethane) ethane, the 2,6-dimethoxyphenol to the potassium hydroxide is 1:(2-2.3):(2.2-2.5), and the volume ratio of ethanol to water is 1:(0.8-1.2). The synthesis method is mainly used for synthesizing the 1,2-di(2-(2,6-dimethoxy phenoxy) ethoxy) ethane.

1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane synthesis method

The present invention discloses a 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane synthesis method, which comprises: (1) stirring at a temperature of 20 DEG C, adding 2,6-dimethoxyphenol and 1,2-(dichloroethane)ethane to acetonitrile, adding potassium hydroxide, carrying a reaction for 90 h at a temperature of 82 DEG C, and evaporating out the acetonitrile to obtain an orange turbid liquid 1; (2) adding dichloromethane to the orange turbid liquid 1, filtering, washing 6 times with 1 M sodium hydroxide, washing twice with saturated sodium chloride, drying with anhydrous magnesium sulfate, and evaporating out the dichloromethane to obtain a yellow oily liquid 2; and (3) adding ether to the yellow oily liquid 2, heating to a temperature of 35 DEG C, filtering out the insoluble matter, cooling to a temperature of 15 DEG C, cooling for 3 h, taking the upper layer solution, cooling to a temperature of 15 DEG C, cooling for 48 h, and filtering to obtain white powder solid 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane. The synthesis method of the present invention is mainly used for the synthesis of 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane.