66227-44-9

Upstream product

• 66227-43-8 4-Butoxy-cyclohexanol 
• 556-48-9 1,4-Cyclohexanediol 
• 22428-87-1 4,4-ethylenedioxycyclohexan-1-ol 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 117960-60-8 2-Acetyl-4-butoxy-cyclohexanone 
• 1130351-34-6 4-butoxy-(2,3-difluorophenyl)cyclohexanol 
• 1130351-36-8 4-butoxy-1-(2,3-difluorphenyl)-cyclohex-1-ene 
• 1130351-38-0 4-(4-butoxycyclohexenyl)-2,3-difluorophenyl boronic acid 
• 1201909-05-8 4-(4-butoxycyclohexenyl)-2,3-difluorophenol 

Relevant academic research and scientific papers

2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS

The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.

Cardiotonic Agents. 1-Methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and Related Compounds. Synthesis and Activity

A series of 1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and related compounds were synthesized and evaluated for positive inotropic activity.Most members of this series exerted a dose-dependent increase in myocardial contractility in the dog acute heart failure model, whereas they caused only slight changes in heart rate and blood pressure.Several derivatives, especially those with cyano, acetyl, and ethyl substituents at the 4-position, were more potent than milrinone, which was used as a reference. 4-Acetyl-1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinone (MS-857) is one of the most potent positive inotropic agents in this series.